Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628483 | 1.00 | EGFR (0.56) | EGFRHDAC3HDAC1HDAC2EPHX1 | |
| SCHEMBL10623848 | 1.00 | EGFR (0.56) | EGFRHDAC3HDAC1HDAC2EPHX1 | |
| SCHEMBL1506756 | 0.98 | EGFR (0.54) | EGFRHDAC3HDAC1HDAC2EPHX1 | |
| SCHEMBL10628647 | 0.93 | HDAC3 (0.51) | EGFRHDAC3HDAC1HDAC2TUBB4A | |
| SCHEMBL10628442 | 0.85 | HDAC3 (0.42) | EGFRHDAC3HDAC1HDAC2ALDH1A1 | |
| SCHEMBL27831000 | 0.82 | EGFR (0.39) | EGFRHDAC3HDAC1HDAC2ALDH1A1 | |
| SCHEMBL9321625 | 0.81 | ESR1 (0.44) | EGFRALDH1A1TP53MAPT | |
| SCHEMBL28579337 | 0.81 | ALOX5 (0.40) | EGFRHDAC3HDAC1HDAC2EPHX1 | |
| SCHEMBL7696990 | 0.79 | EGFR (0.49) | EGFRHDAC3HDAC1HDAC2EPHX1 | |
| (Z)-1,2-Diphenylethene SCHEMBL5489824 | 0.79 | SIGMAR1 (0.61) | EGFRHDAC3NAAASIGMAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1805922-A | Pharmaceutically acceptable salts of carboxylic acid derivatives | ASTRAZENECA AB (SE) | 2006-07-19 | — | — | CN | disclosed |