Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057905 | 0.93 | PTGS2 (0.60) | PTGS2HTR1AHTR1DSLC6A4HTR7 | |
| SCHEMBL15060149 | 0.93 | ALDH1A1 (0.61) | PTGS2HTR1AHTR1DSLC6A4HTR7 | |
| SCHEMBL16382923 | 0.92 | PTGS2 (0.65) | PTGS2HTR1AHTR1DSLC6A4HTR7 | |
| SCHEMBL15073410 | 0.88 | MAPK14 (0.62) | PTGS2HTR1AHTR1DSLC6A4HTR7 | |
| SCHEMBL7039067 | 0.83 | PTGS2 (0.72) | PTGS2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL7042910 | 0.83 | PTGS2 (0.72) | PTGS2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL4816763 | 0.82 | PTGS2 (0.74) | PTGS2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL8856056 | 0.81 | ALOX5 (0.68) | HTR1AHTR1DSLC6A4HTR7HTR5A | |
| SCHEMBL18019742 | 0.81 | ALDH1A1 (0.57) | HTR1AHTR1DSLC6A4HTR7HTR5A | |
| SCHEMBL13399698 | 0.81 | ALOX5 (0.68) | HTR1AHTR1DSLC6A4HTR7HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334275-B2 | Processes for preparing indoles | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-05-10 | — | — | US | disclosed |
| US-20150005494-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-01 | — | — | US | disclosed |
| WO-2013095304-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005494-A1 | PROCESSES FOR PREPARING INDOLES | IDO1, INMT, IDO2 | PTGS2 1000/4885HTR1A 194/4885HTR1D 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.