Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESPL1 | Q14674 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875092 | 0.87 | KMT2A (0.33) | ESPL1ATMTDP1 | |
| SCHEMBL15076282 | 0.81 | — | — | |
| SCHEMBL17875093 | 0.80 | COMT (0.31) | TDP1 | |
| SCHEMBL15075537 | 0.75 | HTT (0.30) | — | |
| SCHEMBL17875097 | 0.75 | GAA (0.43) | — | |
| SCHEMBL15056851 | 0.73 | KMT2A (0.36) | ESPL1ATMTDP1 | |
| SCHEMBL17875095 | 0.73 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL19753291 | 0.66 | TDP1 (0.43) | ESPL1ATMTDP1 | |
| SCHEMBL15056545 | 0.65 | MAPT (0.35) | TDP1 | |
| SCHEMBL19753290 | 0.64 | MAPT (0.37) | ESPL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014202589-A1 | PROCESS FOR MANUFACTURING 4-PROPARGYLATED AMINO-BENZOXAZINONES | BASF SE (DE) | 2014-12-24 | — | — | WO | disclosed |
| WO-2013092856-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013092859-A1 | PROCESS FOR MANUFACTURING 4-SUBSTITUTED AMINO-BENZOXAZINONES | BASF SE (DE) | 2013-06-27 | — | — | WO | disclosed |