Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875095 | 0.90 | SMN1; SMN2 (0.41) | GAAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL15056865 | 0.87 | GAA (0.48) | GAAALDH1A1MAPTGPR174CYP1A2 | |
| SCHEMBL17875092 | 0.78 | KMT2A (0.33) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL15075566 | 0.77 | SMN1; SMN2 (0.46) | GAAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL17875093 | 0.76 | COMT (0.31) | MAPTCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL15075518 | 0.75 | ESPL1 (0.31) | — | |
| SCHEMBL9838538 | 0.67 | GPR174 (0.45) | GAAALDH1A1MAPTGPR174CYP1A2 | |
| SCHEMBL14413902 | 0.66 | PDGFRB (0.42) | ALDH1A1MAPTKDM4ERAB9AHTT | |
| SCHEMBL15056851 | 0.64 | KMT2A (0.36) | GAAALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL19753291 | 0.62 | TDP1 (0.43) | ALDH1A1MAPTCYP1A2CYP3A4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885296-B1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2016-06-29 | — | — | EP | disclosed |