Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833467 | 0.88 | CDYL2 (0.48) | CDYL2CDYLPGRTP53MEN1 | |
| SCHEMBL2299750 | 0.85 | CDYL2 (0.38) | ALDH1A1GAACDYL2CDYLPGR | |
| SCHEMBL9202056 | 0.83 | CES1 (0.43) | TP53 | |
| SCHEMBL13947509 | 0.83 | CDYL2 (0.44) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL15075938 | 0.81 | CACNB4 (0.41) | PGRTP53MEN1KMT2A | |
| SCHEMBL5751031 | 0.79 | MEN1 (0.39) | ALDH1A1KDM4EHSD17B10PGRMAPT | |
| SCHEMBL7681777 | 0.78 | MAPT (0.58) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL28913497 | 0.76 | CDYL2 (0.54) | ALDH1A1GAAHSD17B10CDYL2CDYL | |
| SCHEMBL9830748 | 0.76 | ALDH1A1 (0.34) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL9834567 | 0.75 | ALDH1A1 (0.35) | ALDH1A1KDM4EGAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093928-A1 | AN IMPROVED PROCESS FOR PREPARING 2-OXINDOLES OF FORMULA I, A KEY RAW MATERIAL FOR MAKING PHARMACEUTICAL DRUGS AND INTERMEDIATES THEREOF | ARCH PHARMALABS LIMITED (IN) | 2013-06-27 | — | — | WO | disclosed |