Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075740 | 0.88 | ALDH1A1 (0.43) | CDYL2CDYLMEN1KMT2APGR | |
| SCHEMBL4850477 | 0.82 | MAPT (0.44) | MEN1KMT2ATGM2TP53 | |
| SCHEMBL4270503 | 0.82 | TP53 (0.45) | CDYL2CDYLMEN1KMT2ATP53 | |
| SCHEMBL9202056 | 0.80 | CES1 (0.43) | TP53 | |
| SCHEMBL7681777 | 0.78 | MAPT (0.58) | MEN1KMT2AIDO1TDO2 | |
| SCHEMBL9830748 | 0.76 | ALDH1A1 (0.34) | KMT2A | |
| SCHEMBL9834567 | 0.75 | ALDH1A1 (0.35) | KMT2A | |
| SCHEMBL13947509 | 0.74 | CDYL2 (0.44) | CDYL2CDYLMEN1KMT2APGR | |
| SCHEMBL2299750 | 0.73 | CDYL2 (0.38) | CDYL2CDYLMEN1KMT2APGR | |
| SCHEMBL24112733 | 0.73 | PGR (0.69) | CDYL2CDYLMEN1KMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208510-B1 | 1-SUBSTITUTED OXINDOLE-3-CARBOXAMINES AS ANTIINFLAMMATORY AND ANALGESIC AGENTS | PFIZER INC. (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4791129-A | RHEUMATIC DISEASES; ANTIARTHRITIC AGENTS | PFIZER INC. (US) | 1988-12-13 | — | — | US | disclosed |
| US-4725616-A | ANTIARTHRITIC AGENTS | PFIZER INC. (US) | 1988-02-16 | — | — | US | disclosed |
| EP-0208510-A2 | 1-Substituted oxindole-3-carboxamines as antiinflammatory and analgesic agents | PFIZER INC. (US) | 1987-01-14 | — | — | EP | disclosed |
| CN-86105309-A | Oxindole-3-carbonyl amines the compound that replaces as the 1-of anti-inflammatory and anodyne | — | 1987-01-14 | — | — | CN | disclosed |