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Sugi Predict / Compounds / SCHEMBL15076044

SCHEMBL15076044

SCHEMBL15076044

Oc1cc(O)c2cc1Cc1cc(c(O)cc1O)Cc1cc(c(O)cc1O)Cc1cc(c(O)cc1O)C2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ING2 Q9H160 1/20 0.35
▸ MAPT P10636 3/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ CYP3A4 P08684 2/20 0.33
▸ FYN P06241 1/20 0.33
▸ USP2 O75604 1/20 0.33
▸ HPN P05981 1/20 0.33
▸ ALOX5 P09917 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ PTGS1 P23219 1/20 0.33
▸ PDE4A P27815 1/20 0.33
▸ KDR P35968 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ SIRT5 Q9NXA8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29617578 1.00 ING2 (0.35) ING2MAPTMEN1ALDH1A1KMT2A
SCHEMBL24064901 0.91 FYN (0.40) ING2MAPTMEN1ALDH1A1KMT2A
SCHEMBL29441859 0.89 FYN (0.41) ING2MAPTMEN1ALDH1A1KMT2A
SCHEMBL29308450 0.78 ING2 (0.33) ING2DUSP5DUSP6PTPRB
SCHEMBL23268473 0.76 BACE1 (0.42) ALOX5DRD1
SCHEMBL30525542 0.74 FYN (0.48) ING2MAPTMEN1ALDH1A1KMT2A
SCHEMBL7777089 0.74 FYN (0.48) ING2MAPTMEN1ALDH1A1KMT2A
SCHEMBL24064899 0.73 KDM4E (0.33) ING2MAPTALDH1A1KMT2AKDM4E
SCHEMBL29634901 0.71 ING2 (0.46) ING2MAPTCYP3A4DUSP5DUSP6
SCHEMBL29944381 0.68 CYP3A4 (0.58) MAPTALDH1A1CYP3A4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021120767-A1 BELT[N]ARENE TROPYLIUM COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 清华大学 2021-06-24 — — WO disclosed
US-9375395-B2 Compositions comprising an NFκB-inhibitor and a tropoelastin promoter JOHNSON & JOHNSON CONSUMER INC. (US) 2016-06-28 — — US disclosed
US-9289361-B2 Compositions comprising an NFκB-inhibitor and a non-retinoid collagen promoter JOHNSON & JOHNSON CONSUMER INC. (US) 2016-03-22 — — US disclosed
US-20150064292-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER KENVUE BRANDS LLC 2015-03-05 — — US disclosed
US-8906432-B2 Compositions comprising an NFκB-inhibitor and a non-retinoid collagen promoter JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-12-09 — — US disclosed
US-20130171281-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2013-07-04 — — US disclosed
US-20130164393-A1 Compositions Comprising an NFkB-Inhibitor and a Non-Retinoid Collagen Promoter JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2013-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150064292-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER NFKBIA, NFKB1, NFKB2 ING2 269/4885MAPT 702/4885MEN1 4640/4885
US-20130171281-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER NFKBIA, NFKB1, NFKB2 ING2 269/4885MAPT 702/4885MEN1 4640/4885
US-20130164393-A1 Compositions Comprising an NFkB-Inhibitor and a Non-Retinoid Collagen Promoter NFKBIA, NFRKB, NFKB1 ING2 353/4885MAPT 2768/4885MEN1 4477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.