Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076044 | 0.73 | ING2 (0.35) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL29617578 | 0.73 | ING2 (0.35) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL24064901 | 0.67 | FYN (0.40) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL29308450 | 0.65 | ING2 (0.33) | ING2 | |
| SCHEMBL29441859 | 0.65 | FYN (0.41) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL29634901 | 0.63 | ING2 (0.46) | MAPTING2 | |
| SCHEMBL29944381 | 0.63 | CYP3A4 (0.58) | ALDH1A1MAPT | |
| SCHEMBL29308441 | 0.61 | MAPT (0.39) | KDM4EALDH1A1GAAMAPTRECQL | |
| SCHEMBL29308443 | 0.61 | MAPT (0.39) | KDM4EALDH1A1GAAMAPTRECQL | |
| SCHEMBL29308444 | 0.57 | DRD2 (0.37) | KDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036515-B2 | Thin-film composite membrane and methods of making and using the same | THE PENN STATE RESEARCH FOUNDATION (PA) | 2024-07-16 | — | — | US | disclosed |
| US-20210370240-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | THE PENN STATE RESEARCH FOUNDATION | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036515-B2 | Thin-film composite membrane and methods of making and using the same | PORCN, MLEC, FLOT1 | KDM4E 3071/4885ALDH1A1 4875/4885POLB 3178/4885 |
| US-20210370240-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | PORCN, MLEC, FLOT1 | KDM4E 3071/4885ALDH1A1 4875/4885POLB 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.