SCHEMBL24064901

SCHEMBL24064901

Oc1cc2c(cc1O)Cc1cc(c(O)cc1O)Cc1cc(c(O)cc1O)Cc1cc(c(O)cc1O)C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FYN P06241 3/20 0.40
ADCY6 O43306 1/20 0.40
ADCY3 O60266 1/20 0.40
ADCY9 O60503 1/20 0.40
ADCY5 O95622 1/20 0.40
ADCY8 P40145 1/20 0.40
ADCY7 P51828 1/20 0.40
ADCY2 Q08462 1/20 0.40
ADCY1 Q08828 1/20 0.40
ADCY4 Q8NFM4 1/20 0.40
DRD2 P14416 3/20 0.39
DRD1 P21728 3/20 0.39
DRD5 P21918 3/20 0.39
DRD4 P21917 1/20 0.39
MAPT P10636 4/20 0.33
ALDH1A1 P00352 2/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15076044 0.91 ING2 (0.35) FYNADCY6ADCY3ADCY9ADCY5
SCHEMBL29617578 0.91 ING2 (0.35) FYNADCY6ADCY3ADCY9ADCY5
SCHEMBL7777089 0.87 FYN (0.48) FYNADCY6ADCY3ADCY9ADCY5
SCHEMBL29441859 0.87 FYN (0.41) FYNADCY6ADCY3ADCY9ADCY5
SCHEMBL30525542 0.87 FYN (0.48) FYNADCY6ADCY3ADCY9ADCY5
SCHEMBL29308444 0.86 DRD2 (0.37) FYNADCY6ADCY3ADCY9ADCY5
SCHEMBL29308443 0.76 MAPT (0.39) MAPTALDH1A1HIF1AHSD17B10USP2
SCHEMBL29308441 0.76 MAPT (0.39) MAPTALDH1A1HIF1AHSD17B10USP2
SCHEMBL29308450 0.76 ING2 (0.33) ING2
SCHEMBL7983585 0.73 CA1 (0.42) FYNADCY6ADCY3ADCY9ADCY5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036515-B2 Thin-film composite membrane and methods of making and using the same THE PENN STATE RESEARCH FOUNDATION (PA) 2024-07-16 US disclosed
US-20210370240-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2021-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036515-B2 Thin-film composite membrane and methods of making and using the same PORCN, MLEC, FLOT1 FYN 3831/4885ADCY6 1049/4885ADCY3 581/4885
US-20210370240-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 FYN 3831/4885ADCY6 1049/4885ADCY3 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.