Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133799 | 1.00 | HTR1A (0.36) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL1133830 | 0.87 | ALDH1A1 (0.50) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL15077477 | 0.80 | ALDH1A1 (0.38) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL5307075 | 0.76 | ALDH1A1 (0.47) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL4790647 | 0.76 | ALDH1A1 (0.47) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL5307972 | 0.76 | ALDH1A1 (0.47) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL15077475 | 0.75 | MAPK14 (0.35) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL7964858 | 0.73 | ADRA1B (0.49) | HTR1AADRA1DADRA1AADRA1BTMEM97 | |
| SCHEMBL1133834 | 0.73 | ALDH1A1 (0.43) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL1133835 | 0.73 | ALDH1A1 (0.43) | HTR1AADRA1DADRA1AADRA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130557-A1 | INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF | SYDDANSK UNIVERSITET (DK) | 2011-06-02 | — | — | US | disclosed |
| EP-2285820-A1 | INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF | Syddansk Universitet (DK) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009135890-A1 | INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF | SYDDANSK UNIVERSITET (DK) | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130557-A1 | INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF | POLRMT, DDX1, DDX18 | HTR1A 3966/4885ADRA1D 2026/4885ADRA1A 1760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.