SCHEMBL150785

SCHEMBL150785

CCOP(=O)([O-])Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.CCOP(=O)([O-])Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.[Ca+2]

nearest known ligand 0.58

Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR known ✓ P04035 4/20 0.58
GABBR2 known ✓ O75899 1/20 0.41
GABBR1 known ✓ Q9UBS5 1/20 0.41
NR1I2 O75469 1/20 0.55
KMT2A Q03164 5/20 0.50
GAA P10253 5/20 0.50
MEN1 O00255 4/20 0.50
ALDH1A1 P00352 4/20 0.42
TSHR P16473 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 2/20 0.42
BLM P54132 2/20 0.42
ATM Q13315 2/20 0.42
HIF1A Q16665 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MAPT P10636 2/20 0.42
USP2 O75604 1/20 0.42
CYP2D6 P10635 1/20 0.42
LMNA P02545 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5967420 0.97 HMGCR (0.58) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL916916 0.97 HMGCR (0.58) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL564168 0.97 HMGCR (0.58) HMGCRNR1I2KMT2AGAAMEN1
Lithium Ion SCHEMBL562986 0.97 HMGCR (0.58) HMGCRNR1I2KMT2AGAAMEN1
Potassium Ion SCHEMBL910999 0.97 HMGCR (0.58) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL911829 0.97 HMGCR (0.58) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL1900817 0.97 HMGCR (0.58) HMGCRNR1I2KMT2AGAAMEN1
Zinc Ion SCHEMBL915461 0.97 HMGCR (0.58) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL915239 0.97 HMGCR (0.58) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL563207 0.97 HMGCR (0.58) HMGCRNR1I2KMT2AGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2047 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737511-A1 A POLYAMIDE 6 COMPOSITION AND AN ARTICLE PREPARED THEREFROM Duraflex Hong Kong Limited (HK) 2026-05-06 EP claimed
US-20260117045-A1 POLYAMIDE 6 COMPOSITION AND AN ARTICLE PREPARED THEREFROM DURAFLEX HONG KONG LTD (HK) 2026-04-30 US claimed
US-20260062535-A1 POLYAMIDE 6 COMPOSITION AND AN ARTICLE PREPARED THEREFROM DURAFLEX HONG KONG LTD (HK) 2026-03-05 US claimed
EP-4703417-A1 POLYAMIDE 6 COMPOSITION AND AN ARTICLE PREPARED THEREFROM Duraflex Hong Kong Limited (HK) 2026-03-04 EP claimed
US-20240174839-A1 STABILIZER MIXTURE BASF SE (DE) 2024-05-30 US claimed
EP-4314141-A1 STABILIZER MIXTURE BASF SE (DE) 2024-02-07 EP claimed
US-20230357498-A1 METHOD FOR PREPARING A COPOLYESTER Hanwha Solutions Corporation (KR) 2023-11-09 US claimed
CN-116589835-A Production method of low-cost PET modified alloy transparent tile 安徽荣繁盛新材料科技有限公司 2023-08-15 CN claimed
EP-4219587-A1 METHOD FOR PRODUCING COPOLYESTER Hanwha Solutions Corporation (KR) 2023-08-02 EP claimed
EP-3122819-B1 MELT POLYMERIZATION POLYCARBONATE QUENCHING TECHNICAL FIELD SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-07-19 EP claimed
US-4717748-A STABILIZING AGAINST OXIDATIVE, THERMAL AND ACTINIC DEGRADATION; USED WITH PHENOLIC ANTIOXIDANTS CIBA-GEIGY CORPORATION (US) 1988-01-05 US claimed
US-4703073-A DISCOLORATION INHIBITION CIBA-GEIGY CORPORATION (US) 1987-10-27 US claimed
US-4696964-A HEAT RESISTANCE, OXIDATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1987-09-29 US claimed
US-4673700-A Amide substituted benzylhydroxylamines and stabilized polyolefin compositions CIBA-GEIGY CORPORATION (US) 1987-06-16 US claimed
US-4668721-A PHOSPHITE, HINDERED AMINE, PHENOLIC ANTIOXIDANT CIBA-GEIGY CORPORATION (US) 1987-05-26 US claimed
US-4668727-A Ester substituted benzylhydroxylamines and stabilized polyolefin compositions CIBA-GEIGY CORPORATION (US) 1987-05-26 US claimed
US-4663373-A Compositions stabilized with substituted aminoxy silanes CIBA-GEIGY CORPORATION (US) 1987-05-05 US claimed
US-4659514-A Esterification of rosin acid with calcium hydroxybenzyl phosphonate catalyst CIBA-GEIGY CORPORATION (US) 1987-04-21 US claimed
US-4612393-A Bis(substituted thioalkyl)hydroxylamines and stabilized polyolefin compositions CIBA-GEIGY CORPORATION (US) 1986-09-16 US claimed
US-4590231-A DISCOLORATION INHIBITION CIBA-GEIGY CORPORATION (US) 1986-05-20 US claimed