Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29031390 | 0.83 | ALDH1A1 (0.54) | IDO1TDO2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29031396 | 0.79 | ALDH1A1 (0.39) | IDO1TDO2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1507854 | 0.79 | ALDH1A1 (0.53) | IDO1TDO2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5052368 | 0.77 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2LMNAHTTHPGD | |
| Fluorobenzene SCHEMBL1444304 | 0.74 | ALDH1A1 (0.69) | IDO1TDO2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL25482200 | 0.73 | IDO1 (0.56) | IDO1TDO2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL30910880 | 0.73 | IDO1 (0.56) | IDO1TDO2SMN1; SMN2HTTCYP3A4 | |
| SCHEMBL14814262 | 0.73 | IDO1 (0.56) | IDO1TDO2SMN1; SMN2HTTCYP3A4 | |
| SCHEMBL181005 | 0.72 | TSHR (0.56) | ALDH1A1SMN1; SMN2LMNAHTTHPGD | |
| SCHEMBL24804931 | 0.71 | IDO1 (0.54) | IDO1TDO2CYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911740-B1 | POTASSIUM CHANNEL MODULATORS | NEUROSEARCH AS (DK) | 2013-02-27 | — | — | EP | disclosed |
| EP-2292595-A1 | Potassium channel modulators | NeuroSearch AS (DK) | 2011-03-09 | — | — | EP | disclosed |
| US-7429618-B2 | Potassium channel modulators | NEUROSEARCH A/S (DK) | 2008-09-30 | — | — | US | disclosed |
| EP-1465863-B1 | POTASSIUM CHANNEL MODULATORS | NEUROSEARCH AS (DK) | 2008-07-09 | — | — | EP | disclosed |
| EP-1911740-A1 | POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2008-04-16 | — | — | EP | disclosed |
| US-20070161607-A1 | Potassium channel modulators | SANIONA A/S (DK) | 2007-07-12 | — | — | US | disclosed |
| US-7208527-B2 | Potassium channel modulators | POSEIDON PHARMACEUTICALS A/S (DK) | 2007-04-24 | — | — | US | disclosed |
| US-20050009816-A1 | Potassium channel modulators | SANIONA A/S (DK) | 2005-01-13 | — | — | US | disclosed |
| EP-1465863-A1 | POTASSIUM CHANNEL MODULATORS | Poseidon Pharmaceuticals A/S (DK) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003059873-A1 | POTASSIUM CHANNEL MODULATORS | POSEIDON PHARMACEUTICALS A/S (DK) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009816-A1 | Potassium channel modulators | KCNC1, KCNQ1, KCNA1 | IDO1 2700/4885TDO2 4093/4885ALDH1A1 3877/4885 |
| US-20070161607-A1 | Potassium channel modulators | KCNC1, KCNQ1, KCNA1 | IDO1 2700/4885TDO2 4093/4885ALDH1A1 3877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.