Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307398 | 0.97 | TSHR (0.54) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13198785 | 0.97 | ALDH1A1 (0.58) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL27539023 | 0.97 | TSHR (0.54) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL909586 | 0.97 | TSHR (0.54) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| Acetonitrile SCHEMBL28159901 | 0.92 | ALDH1A1 (0.55) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28381532 | 0.90 | ALDH1A1 (0.49) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5773518 | 0.86 | ALDH1A1 (0.50) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7995238 | 0.86 | SLC6A2 (0.58) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9447402 | 0.86 | ALDH1A1 (0.54) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5164828 | 0.86 | L3MBTL1 (0.56) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398100-B2 | Methods and intermediates for preparing hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide | MYLAN LABORATORIES LIMITED (IN) | 2025-08-26 | — | — | US | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| CN-119431386-A | Synthesis method of 2'- (trifluoromethyl) -4, 5-dihydro-spiro [ furan-2, 3' -indoline ] derivative | 西北师范大学 | 2025-02-14 | — | — | CN | claimed |
| CN-118271580-B | Anion exchange membrane prepared from aryl piperidine copolymer containing triazine ring branched structure, preparation method and application | 大连理工大学 | 2024-08-16 | — | — | CN | claimed |
| US-20240217919-A1 | NOVEL METHODS FOR SYNTHESIZING ENANTIOPURE (S)-METHADONE, (R)-METHADONE, RACEMIC (R,S)-METHADONE AND RELATED ANALOGUE SUBSTANCES | MANFREDI PAOLO L (US) | 2024-07-04 | — | — | US | claimed |
| CN-118271580-A | Anion exchange membrane prepared from aryl piperidine copolymer containing triazine ring branched structure, preparation method and application | 大连理工大学 | 2024-07-02 | — | — | CN | claimed |
| WO-2024115722-A1 | ASYMMETRICAL PHENYLENE BIS IMIDES AND THEIR PREPARATION | ARXADA AG (CH) | 2024-06-06 | — | — | WO | claimed |
| CN-117897146-A | Novel process for synthesizing enantiomerically pure (S) -methadone, (R) -methadone, racemic (R, S) -methadone and related analogues | 保罗·L·曼佛雷蒂 | 2024-04-16 | — | — | CN | claimed |
| EP-4319733-A1 | NOVEL METHODS FOR SYNTHETIZING ENANTIOPURE (S)-METHADONE, (R)-METHADONE, RACEMIC (R,S)-METHADONE AND RELATED ANALOGUE SUBSTANCES | Manfredi, Paolo L. (US) | 2024-02-14 | — | — | EP | claimed |
| CN-116283783-A | Preparation method of imidafenacin | 南京联智医药科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-5441743-A | In thermoplastic or thermosetting binder | BATTELLE MEMORIAL INSTITUTE (US) | 1995-08-15 | — | — | US | claimed |
| CN-1019571-B | Process for preparing biphenyl-n-propylamine derivatives and their salts | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1992-12-23 | — | — | CN | claimed |
| EP-0253327-B1 | DIPHENYLPROPYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-05-06 | — | — | EP | claimed |
| WO-1990006975-A1 | NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS | BATTELLE MEMORIAL INSTITUTE (US) | 1990-06-28 | — | — | WO | claimed |
| CN-87104753-A | Prepare the new diphenyl Tri N-Propyl Amine derivative and the method for salt thereof | — | 1988-06-15 | — | — | CN | claimed |
| EP-0253327-A2 | Diphenylpropylamine derivatives, their preparation and their pharmaceutical use | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-01-20 | — | — | EP | claimed |
| EP-0178946-A2 | 1-(Aminoalkyl)-alpha, alpha-diaryl pyrrolidine-piperidine- and homopiperidine- acetamides and acetonitriles | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-04-23 | — | — | EP | claimed |
| US-4307034-A | ALKYLATION | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-12-22 | — | — | US | claimed |
| US-4242274-A | DIPHENYLACETONITRILE, 1-(DIMETHYLAMINO)-2-HALOPROPANE, A BASE, WATER, A SOLVENT, AND A QUATERNARY CATALYST | MALLINCKRODT, INC. (US) | 1980-12-30 | — | — | US | claimed |
| US-4048211-A | Modification of methadone synthesis process step | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217919-A1 | NOVEL METHODS FOR SYNTHESIZING ENANTIOPURE (S)-METHADONE, (R)-METHADONE, RACEMIC (R,S)-METHADONE AND RELATED ANALOGUE SUBSTANCES | OPRM1, OPRD1, OPRK1 | TSHR 1369/4885TRPA1 1547/4885ALDH1A1 405/4885 |
| US-12398100-B2 | Methods and intermediates for preparing hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide | HPD, AZI2, HDHD5 | TSHR 3882/4885TRPA1 2924/4885ALDH1A1 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.