Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15078737 | 1.00 | PLA2G4B (0.33) | PLA2G4BSMN1; SMN2KDM4ELMNACYP1A2 | |
| SCHEMBL15074935 | 1.00 | PLA2G4B (0.33) | PLA2G4BSMN1; SMN2KDM4ELMNACYP1A2 | |
| SCHEMBL15078733 | 0.87 | LMNA (0.36) | SMN1; SMN2KDM4ELMNACYP1A2KMT2A | |
| SCHEMBL15077383 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4ELMNACYP1A2ALDH1A1 | |
| SCHEMBL15077404 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4ELMNACYP1A2ALDH1A1 | |
| SCHEMBL15077401 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4ELMNACYP1A2ALDH1A1 | |
| SCHEMBL13073613 | 0.86 | ALDH1A1 (0.39) | SMN1; SMN2CYP1A2MEN1KMT2ALPL | |
| SCHEMBL5019553 | 0.86 | ALDH1A1 (0.43) | SMN1; SMN2CYP1A2MEN1KMT2ALPL | |
| SCHEMBL15078712 | 0.85 | LPL (0.34) | SMN1; SMN2LPLLIPGALDH1A1HPGD | |
| SCHEMBL15074985 | 0.85 | ALDH1A1 (0.41) | SMN1; SMN2KDM4ECYP1A2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530452-B2 | Tricyclic boron compounds for antimicrobial therapy | MICURX PHARMACEUTICALS, INC. (KY) | 2013-09-10 | — | — | US | disclosed |
| US-20130165411-A1 | TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY | MICURX PHARMACEUTICALS, INC. (KY) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165411-A1 | TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY | TBCA, TBCB, BTD | PLA2G4B 4870/4885SMN1; SMN2 1879/4885KDM4E 4661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.