SCHEMBL15079871

SCHEMBL15079871

COc1ccc(OCCc2ccccc2O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
HPGD P15428 1/20 0.51
ATM Q13315 1/20 0.51
RAB9A P51151 3/20 0.50
PKM P14618 2/20 0.50
NPC1 O15118 2/20 0.50
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
GAA P10253 1/20 0.47
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
DRD3 P35462 1/20 0.46
KCNH2 Q12809 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
TAAR1 Q96RJ0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15079410 0.86 CYP4F2 (0.49) MAPTL3MBTL1RAB9ANPC1CYP4F2
SCHEMBL15079867 0.86 MEN1 (0.51) MAPTL3MBTL1HPGDCYP4F2CYP4A11
SCHEMBL16368719 0.86 CYP4F2 (0.51) CYP4F2CYP4A11LMNADRD2DRD4
SCHEMBL9854724 0.85 KCNA3 (0.52) RAB9APKMNPC1CYP4F2CYP4A11
SCHEMBL15079796 0.85 MAPK1 (0.50) L3MBTL1ATMRAB9APKMNPC1
SCHEMBL9854722 0.84 MPO (0.51) MAPTL3MBTL1RAB9ANPC1CYP4F2
SCHEMBL15079368 0.83 CYP4F2 (0.47) MAPTL3MBTL1HPGDATMCYP4F2
SCHEMBL15079379 0.83 RAB9A (0.59) MAPTL3MBTL1RAB9ANPC1CYP4F2
SCHEMBL15079888 0.83 PTGER4 (0.51) CYP4F2CYP4A11KCNH2TAAR1ALDH1A1
SCHEMBL15079855 0.83 CYP4F2 (0.49) L3MBTL1RAB9ANPC1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
WO-2013093320-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS ARG1, TYR, NOS1 MAPT 3297/4885L3MBTL1 719/4885HPGD 84/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.