Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL228601 | 0.84 | NR4A2 (0.51) | KMT2AALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL18765453 | 0.82 | HRH2 (0.44) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL15910890 | 0.81 | LMNA (0.54) | KMT2AALDH1A1LMNASMN1; SMN2SLC6A2 | |
| SCHEMBL23876186 | 0.78 | NPC1 (0.49) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL3045824 | 0.78 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL23876180 | 0.78 | KMT2A (0.50) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5732752 | 0.78 | RAB9A (0.51) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL13313606 | 0.77 | MAOB (0.59) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL12021937 | 0.76 | HSD17B3 (0.49) | ALDH1A1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1502290 | 0.76 | MEN1 (0.51) | KMT2AMEN1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476445-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2013-07-02 | — | — | US | disclosed |