SCHEMBL15080671

SCHEMBL15080671

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(OC(=O)Oc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.48
ALDH1A1 P00352 3/20 0.47
LMNA P02545 1/20 0.44
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
MAPT P10636 4/20 0.41
TDP1 Q9NUW8 4/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
PTGES O14684 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KDM4E B2RXH2 1/20 0.40
THRB P10828 1/20 0.40
GFER P55789 1/20 0.40
PTK2B Q14289 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17473038 0.87 LMNA (0.53) USP2ALDH1A1LMNAPPARGPPARA
SCHEMBL97469 0.85 USP2 (0.60) USP2ALDH1A1LMNAMAPTL3MBTL1
SCHEMBL237315 0.83 LMNA (0.61) USP2ALDH1A1LMNAPPARGPPARA
SCHEMBL10102829 0.82 THRB (0.46) ALDH1A1LMNAPPARGPPARAMAPT
SCHEMBL9915724 0.82 THRB (0.46) ALDH1A1LMNAPPARGPPARAMAPT
SCHEMBL9915728 0.82 ALDH1A1 (0.46) ALDH1A1LMNAPPARGPPARATDP1
SCHEMBL172431 0.82 ALDH1A1 (0.46) ALDH1A1LMNAPPARGPPARATDP1
SCHEMBL12751438 0.82 ELANE (0.52) ALDH1A1LMNAPPARGPPARAMAPT
SCHEMBL12149085 0.82 ALDH1A1 (0.46) ALDH1A1LMNAPPARGPPARATDP1
SCHEMBL9915700 0.82 ALDH1A1 (0.46) ALDH1A1LMNAPPARGPPARATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475982-B2 Charge-transporting compound, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed
US-8475982-B2 Charge-transporting compound, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed