Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755830 | 0.83 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL16202052 | 0.82 | SMN1; SMN2 (0.47) | L3MBTL1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL28545074 | 0.82 | NPC1 (0.56) | L3MBTL1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL25923625 | 0.82 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL678711 | 0.81 | MAPT (0.57) | L3MBTL1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL15504890 | 0.80 | IDO1 (0.52) | SMN1; SMN2NPC1RAB9APOLBKDM4E | |
| SCHEMBL23368002 | 0.77 | NPC1 (0.68) | L3MBTL1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL15631237 | 0.77 | RXRA (0.51) | SMN1; SMN2NPC1RAB9ARXRARXRB | |
| SCHEMBL1405999 | 0.77 | ALDH1A1 (0.39) | L3MBTL1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL25923630 | 0.73 | MAOB (0.49) | L3MBTL1SMN1; SMN2NPC1RAB9ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476411-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2013-07-02 | — | — | US | disclosed |