SCHEMBL15082104

SCHEMBL15082104

C[S+]([O-])CC(=O)OC(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.33
DGAT1 O75907 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14307495 0.80 CYP2D6 (0.32) CYP2D6DGAT1HDAC3HDAC1HDAC2
SCHEMBL16139487 0.80 CYP2D6 (0.32) CYP2D6DGAT1HDAC3HDAC1HDAC2
Bromide SCHEMBL11395572 0.79 DGAT1 (0.33) CYP2D6DGAT1HDAC3HDAC1HDAC2
SCHEMBL16141690 0.78 CA12 (0.33) CYP2D6DGAT1HDAC3HDAC1HDAC2
SCHEMBL12040169 0.78 DGAT1 (0.34) CYP2D6DGAT1HDAC3HDAC1HDAC2
SCHEMBL2930861 0.73
SCHEMBL20694270 0.71 NR1D1 (0.32)
SCHEMBL14089793 0.70 DGAT1 (0.37) DGAT1CA12CA2CA14
SCHEMBL20892278 0.70 MTNR1A (0.37) CA12CA14
SCHEMBL644646 0.69 TSHR (0.45) CYP2D6DGAT1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100158-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD, EACH USING THE SAME FUJIFILM CORPORATION (JP) 2013-07-04 WO disclosed