SCHEMBL15083040

SCHEMBL15083040

CNC(=O)O[C@H](c1ccc(Cl)cc1Cl)[C@H](O)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
TP53 P04637 1/20 0.41
HTT P42858 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
FFAR2 O15552 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14477704 0.83 LMNA (0.46) LMNATP53HTTMEN1KMT2A
SCHEMBL14477708 0.83 LMNA (0.46) LMNATP53HTTMEN1KMT2A
SCHEMBL14477702 0.83 LMNA (0.46) LMNATP53HTTMEN1KMT2A
SCHEMBL15082997 0.81 L3MBTL1 (0.43) LMNATP53HTTMEN1KMT2A
SCHEMBL15087392 0.75 ALDH1A1 (0.37) MEN1KMT2AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL23347549 0.71 LMNA (0.49) LMNATP53HTTMEN1KMT2A
SCHEMBL3435809 0.71 ADRB2 (0.42) LMNAALDH1A1SMN1; SMN2
SCHEMBL14477707 0.71 LMNA (0.49) LMNATP53HTTMEN1KMT2A
SCHEMBL3434987 0.71 ADRB2 (0.42) LMNAALDH1A1SMN1; SMN2
SCHEMBL14477675 0.71 ADRB2 (0.42) LMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100569-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING MULTIPLE SCLEROSIS BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed