Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11309314 | 1.00 | CYP3A4 (0.52) | CYP3A4TSHRALDH1A1CYP1A2KMT2A | |
| SCHEMBL11627982 | 0.88 | ERCC1 (0.48) | CYP3A4TSHRALDH1A1CYP1A2KMT2A | |
| SCHEMBL340537 | 0.88 | AKR1C3 (0.55) | ALDH1A1KMT2AMEN1AKR1C3MAPT | |
| Phenol SCHEMBL9660796 | 0.84 | ERCC1 (0.49) | ALDH1A1KMT2AMEN1AKR1C3HIF1A | |
| SCHEMBL214885 | 0.83 | SYK (0.57) | CYP3A4TSHRALDH1A1CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL8170506 | 0.82 | ALDH1A1 (0.50) | CYP3A4TSHRALDH1A1CYP1A2KMT2A | |
| SCHEMBL3210538 | 0.81 | ALDH1A1 (0.50) | CYP3A4TSHRALDH1A1CYP1A2KMT2A | |
| SCHEMBL21834459 | 0.80 | ALDH1A1 (0.51) | CYP3A4TSHRALDH1A1CYP1A2KMT2A | |
| SCHEMBL6904254 | 0.80 | ALDH1A1 (0.51) | CYP3A4TSHRALDH1A1CYP1A2KMT2A | |
| SCHEMBL11319121 | 0.80 | SYK (0.59) | CYP3A4TSHRALDH1A1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12156879-B2 | Combining BACE1 inhibitors with mGluR agonists for Alzheimer's disease therapy | UNIVERSITY OF CONNECTICUT (US) | 2024-12-03 | — | — | US | claimed |
| US-20210161910-A1 | Combining BACE1 Inhibitors With mGluR Agonists For Alzheimer's Disease Therapy | UNIVERSITY OF CONNECTICUT | 2021-06-03 | — | — | US | claimed |
| CN-101906052-B | Method for preparing D-m-hydroxyphenylglycine | SHANGHAI BAOSTEEL CHEMICAL CO | 2013-10-30 | — | — | CN | claimed |
| US-8053585-B2 | Protecting group for carboxylic acids that can be photolyzed by visible light | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-11-08 | — | — | US | claimed |
| US-20110263652-A1 | Treatment and/or Prevention of Inner Ear Conditions by Modulation of a Metabotropic Glutamate Receptor | HOUSE EAR INSTITUTE (US) | 2011-10-27 | — | — | US | claimed |
| EP-2344151-A2 | TREATMENT AND/OR PREVENTION OF INNER EAR CONDITIONS BY MODULATION OF A METABOTROPIC GLUTAMATE RECEPTOR | HOUSE EAR INSTITUTE (US) | 2011-07-20 | — | — | EP | claimed |
| CN-102115478-A | Furo-indole compounds and preparation method and application thereof | UNIV SHANGHAI OCEAN | 2011-07-06 | — | — | CN | claimed |
| CN-101906052-A | Method for preparing D-m-hydroxyphenylglycine | SHANGHAI BAOSTEEL CHEMICAL CO | 2010-12-08 | — | — | CN | claimed |
| WO-2010048095-A2 | TREATMENT AND/OR PREVENTION OF INNER EAR CONDITIONS BY MODULATION OF A METABOTROPIC GLUTAMATE RECEPTOR | HOUSE EAR INSTITUTE (US) | 2010-04-29 | — | — | WO | claimed |
| US-20070243519-A1 | Protecting group for carboxylic acids that can be photolyzed by visible light | CORNELL RESEARCH FOUNDATION, INC. (US) | 2007-10-18 | — | — | US | claimed |
| US-20040138204-A1 | Compositions and methods for pain reduction | RHODE ISLAND HOSPITAL | 2004-07-15 | — | — | US | claimed |
| WO-2004039247-A2 | COMPOSITIONS AND METHODS FOR PAIN REDUCTION | RHODE ISLAND HOSPITAL (US) | 2004-05-13 | — | — | WO | claimed |
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | YU RUEY J (US) | 2003-06-12 | — | — | US | claimed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | claimed |
| US-5587509-A | Caged caboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-12-24 | — | — | US | claimed |
| US-5430175-A | Caged carboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-07-04 | — | — | US | claimed |
| WO-1995015305-A1 | CAGED CARVOXYL COMPOUNDS AND THEIR USE IN CHEMICAL KINETIC INVESTIGATION OF NEUROTRANSMITTER RECEPTORS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-06-08 | — | — | WO | claimed |
| EP-0324943-B1 | WATER SOLUBLE BLACK TRISAZO DYES | CASSELLA Aktiengesellschaft (DE) | 1992-07-22 | — | — | EP | claimed |
| US-4917731-A | Water-soluble black trisazo dyestuffs | CASSELLA AKTIENGESELLSCHAFT (DE) | 1990-04-17 | — | — | US | claimed |
| EP-0324943-A2 | Water soluble black trisazo dyes | CASSELLA Aktiengesellschaft (DE) | 1989-07-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | GRHPR, ARL1, SUCLG1 | CYP3A4 4050/4885TSHR 3740/4885ALDH1A1 1110/4885 |
| US-12156879-B2 | Combining BACE1 inhibitors with mGluR agonists for Alzheimer's disease therapy | BACE1, PSEN1, PSEN2 | CYP3A4 4839/4885TSHR 2181/4885ALDH1A1 4425/4885 |
| US-20210161910-A1 | Combining BACE1 Inhibitors With mGluR Agonists For Alzheimer's Disease Therapy | BACE1, PSEN1, PSEN2 | CYP3A4 4839/4885TSHR 2181/4885ALDH1A1 4425/4885 |
| US-20070243519-A1 | Protecting group for carboxylic acids that can be photolyzed by visible light | CYBA, ALDH3A1, HCCS | CYP3A4 405/4885TSHR 4627/4885ALDH1A1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.