Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 19/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084110 | 0.88 | CTSC (0.53) | CTSCKCNH2CTSK | |
| SCHEMBL15081674 | 0.87 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL15083925 | 0.86 | CTSC (0.39) | CTSC | |
| SCHEMBL15084024 | 0.85 | CTSC (0.48) | CTSCKCNH2CTSK | |
| SCHEMBL15084115 | 0.85 | CTSC (0.48) | CTSCKCNH2CTSK | |
| SCHEMBL15083933 | 0.85 | CTSC (0.51) | CTSC | |
| SCHEMBL15083999 | 0.84 | CTSK (0.43) | CTSCKCNH2CTSK | |
| SCHEMBL14822339 | 0.84 | CTSC (0.48) | CTSCCTSK | |
| SCHEMBL15084106 | 0.83 | CTSC (0.54) | CTSCCTSK | |
| SCHEMBL15084105 | 0.82 | CTSC (0.55) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130172327-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL] -2-AZABICYCLO [2.2.1] HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172327-A1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL] -2-AZABICYCLO [2.2.1] HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | CTSS, CTSB, CTSG | CTSC 9/4885KCNH2 2367/4885CTSK 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.