Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15064902 | 0.86 | MAPT (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15065223 | 0.84 | MAPT (0.44) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21704503 | 0.76 | HSP90AA1 (0.57) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23162599 | 0.75 | ADORA2A (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13733291 | 0.74 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21460575 | 0.73 | TDP1 (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21460544 | 0.68 | KDM4E (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3682872 | 0.67 | MAPT (0.42) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30463636 | 0.66 | POLB (0.53) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL929525 | 0.66 | ADORA2A (0.56) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877925-B2 | 2,6-dihalo-5-alkoxy-4-substituted-pyrimidines, pyrimidine-carbaldehydes, and methods of formation and use | DOW AGROSCIENCES, LLC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-20130172557-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DOW AGROSCIENCES LLC (US) | 2013-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172557-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DPYD, DDT, DCTD | KDM4E 1515/4885ALDH1A1 185/4885MAPT 3654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.