SCHEMBL1508461

SCHEMBL1508461

C=C(C)C(=O)Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.56
NPSR1 Q6W5P4 5/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
ALDH1A1 P00352 1/20 0.56
MAPT P10636 4/20 0.43
HTT P42858 3/20 0.43
UBE2N P61088 2/20 0.43
GLA P06280 1/20 0.43
MITF O75030 1/20 0.43
RAB9A P51151 3/20 0.40
RAD52 P43351 2/20 0.40
STAT3 P40763 1/20 0.40
RCE1 Q9Y256 1/20 0.40
APAF1 O14727 1/20 0.40
HSP90AA1 P07900 1/20 0.40
NOD2 Q9HC29 1/20 0.40
RARG P13631 3/20 0.38
RXRA P19793 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1636868 0.87 MAPK1 (0.60) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11798641 0.86 KMT2A (0.41) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL1953482 0.85 MAPK1 (0.62) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL28378699 0.82 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8145475 0.82 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL1508563 0.82 MAPK1 (0.55) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL30692205 0.81 ATM (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL5143775 0.80 MAPK1 (0.56) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL28208150 0.80 MAPK1 (0.56) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL2449720 0.79 NPSR1 (0.55) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7956115-B2 Phenyl acrylate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-07 US disclosed
EP-2060558-B1 Phenyl acrylate derivatives and their use for producing optical films by means of photopolymerisation SUMITOMO CHEMICAL CO (JP) 2011-03-02 EP disclosed
EP-2060558-A1 Phenyl acrylate derivatives and their use for producing optical films by means of photopolymerisation Sumitomo Chemical Company, Limited (JP) 2009-05-20 EP disclosed
US-20090118407-A1 Phenyl acrylate SUMITOMO CHEMICAL COMPANY, LIMITED 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118407-A1 Phenyl acrylate CRY1, ALKBH5, PAH MAPK1 2288/4885NPSR1 4603/4885SMN1; SMN2 4781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.