SCHEMBL1508563

SCHEMBL1508563

C=CC(=O)Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.55
NPSR1 Q6W5P4 5/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
ALDH1A1 P00352 1/20 0.55
MAPT P10636 4/20 0.43
HTT P42858 3/20 0.43
UBE2N P61088 2/20 0.43
GLA P06280 1/20 0.43
MITF O75030 1/20 0.43
THRB P10828 3/20 0.39
THRA P10827 1/20 0.39
RAB9A P51151 3/20 0.39
RAD52 P43351 2/20 0.39
STAT3 P40763 1/20 0.39
RCE1 Q9Y256 1/20 0.39
APAF1 O14727 1/20 0.39
HSP90AA1 P07900 1/20 0.39
NOD2 Q9HC29 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11798569 0.86 ALDH1A1 (0.40) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL1953482 0.84 MAPK1 (0.62) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL1636868 0.82 MAPK1 (0.60) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL28745620 0.82 MAPK1 (0.42) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL1508461 0.82 MAPK1 (0.56) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL25367674 0.81 THRB (0.51) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8145475 0.81 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL28378699 0.81 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL28797235 0.81 THRB (0.53) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL29500385 0.80 APEX1 (0.46) MAPK1NPSR1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115340836-A Optical adhesive tape and preparation method thereof 广东东立新材料科技股份有限公司 2022-11-15 CN claimed
EP-3455267-B1 IMPROVED PERFORMANCE HIGH VINYL BLOCK COPOLYMER COMPOSITIONS AND USES THEREOF KRATON POLYMERS US LLC (US) 2024-12-04 EP disclosed
CN-114051513-B Polyvinyl alcohol film, stretched film, polarizing film, and method for producing polyvinyl alcohol film 株式会社可乐丽 2024-10-18 CN disclosed
CN-118119662-A Conductive resin composition 阪田油墨股份有限公司 2024-05-31 CN disclosed
CN-117957494-A Resin composition, light-shielding film, and substrate with partition wall 东丽株式会社 2024-04-30 CN disclosed
CN-115279828-B Styrene butadiene block copolymers with low degree of crosslinking 英力士苯领集团股份公司 2024-04-12 CN disclosed
CN-114127194-B Silicone rubber composition, crosslinked silicone rubber, and sealing material 住友理工株式会社 2023-02-28 CN disclosed
CN-115340836-A Optical adhesive tape and preparation method thereof 广东东立新材料科技股份有限公司 2022-11-15 CN disclosed
WO-2022168804-A1 UNDERCOAT AGENT COMPOSITION FOR INORGANIC SUBSTANCE LAYER LAMINATION, CURED PRODUCT THEREOF, AND METHOD FOR PRODUCING SAME 東亞合成株式会社 2022-08-11 WO disclosed
WO-2022114072-A1 CRYSTALLIZATION INHIBITOR FOR POLYOLEFIN RESIN, POLYOLEFIN RESIN COMPOSITION, MOLDED ARTICLE, METHOD FOR PRODUCING POLYOLEFIN RESIN COMPOSITION, AND METHOD FOR INHIBITING CRYSTALLIZATION OF POLYOLEFIN RESIN 株式会社ADEKA 2022-06-02 WO disclosed
WO-2022071051-A1 MALEIMIDE COPOLYMER デンカ株式会社 2022-04-07 WO disclosed
WO-2022071050-A1 PRODUCTION METHOD FOR HEAT-RESISTANT RESIN COMPOSITION デンカ株式会社 2022-04-07 WO disclosed
CN-111433303-A Radical polymerizable adhesive composition for bonding laminated steel sheets, bonded laminate, motor, and method for producing bonded laminate 三键有限公司 2020-07-17 CN disclosed
CN-108699291-A RESIN ADDITIVE COMPOSITION, THERMOPLASTIC RESIN COMPOSITION, AND MOLDED ARTICLE THEREOF 株式会社ADEKA 2018-10-23 CN disclosed
CN-104185644-A Ethylene Polymerization Process Using Inhibitors BOREALIS AG 2014-12-03 CN disclosed
US-7956115-B2 Phenyl acrylate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-07 US disclosed
EP-2060558-B1 Phenyl acrylate derivatives and their use for producing optical films by means of photopolymerisation SUMITOMO CHEMICAL CO (JP) 2011-03-02 EP disclosed
EP-2060558-A1 Phenyl acrylate derivatives and their use for producing optical films by means of photopolymerisation Sumitomo Chemical Company, Limited (JP) 2009-05-20 EP disclosed
US-20090118407-A1 Phenyl acrylate SUMITOMO CHEMICAL COMPANY, LIMITED 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118407-A1 Phenyl acrylate CRY1, ALKBH5, PAH MAPK1 2288/4885NPSR1 4603/4885SMN1; SMN2 4781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.