Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522216 | 0.85 | PARP1 (0.50) | L3MBTL1POLBSMN1; SMN2GLAPARP1 | |
| SCHEMBL1508794 | 0.84 | PARP1 (0.46) | L3MBTL1POLBPARP1ALDH1A1KDM4E | |
| SCHEMBL1508488 | 0.80 | L3MBTL1 (0.61) | RXRARXRBRXRGL3MBTL1POLB | |
| SCHEMBL7520364 | 0.73 | LTB4R (0.46) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL2319086 | 0.71 | ALDH1A1 (0.36) | L3MBTL1POLBALDH1A1KDM4E | |
| SCHEMBL4577451 | 0.69 | PTGDR2 (0.56) | POLBSMN1; SMN2FFAR4RORCPTGDR2 | |
| SCHEMBL340762 | 0.67 | L3MBTL1 (0.80) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL29682135 | 0.67 | L3MBTL1 (0.80) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| Ammonia Solution, Strong SCHEMBL28240461 | 0.66 | L3MBTL1 (0.77) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL74333 | 0.66 | MAPT (0.51) | PARP1KDM4EMRGPRX4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289868-B1 | CARBOXYLIC ACID COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2014-08-13 | — | — | EP | disclosed |
| US-8222281-B2 | Carboxylic acid compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-07-17 | — | — | US | disclosed |
| EP-2289868-A1 | CARBOXYLIC ACID COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2011-03-02 | — | — | EP | disclosed |