Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26650445 | 0.81 | NOTUM (0.41) | CYP11B1CYP11B2EPAS1S1PR1 | |
| SCHEMBL30748004 | 0.81 | NOTUM (0.41) | CYP11B1CYP11B2EPAS1S1PR1 | |
| SCHEMBL9277855 | 0.81 | CYP11B1 (0.40) | CYP11B1CYP11B2NR3C2S1PR1 | |
| SCHEMBL9274574 | 0.78 | CYP11B1 (0.38) | CYP11B1CYP11B2EPAS1NR3C2 | |
| SCHEMBL35211487 | 0.75 | CYP11B1 (0.37) | CYP11B1CYP11B2EPAS1NR3C2S1PR1 | |
| SCHEMBL9282806 | 0.75 | HTR2A (0.40) | CYP11B1CYP11B2EPAS1NR3C2 | |
| SCHEMBL15287108 | 0.75 | CYP11B1 (0.37) | CYP11B1CYP11B2EPAS1NR3C2S1PR1 | |
| SCHEMBL15021555 | 0.75 | CYP11B1 (0.37) | CYP11B1CYP11B2EPAS1NR3C2S1PR1 | |
| SCHEMBL1154471 | 0.74 | DRD2 (0.44) | CYP11B1CYP11B2NR3C2 | |
| SCHEMBL28003136 | 0.74 | DRD2 (0.44) | CYP11B1CYP11B2NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289868-B1 | CARBOXYLIC ACID COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2014-08-13 | — | — | EP | disclosed |
| US-8222281-B2 | Carboxylic acid compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-07-17 | — | — | US | disclosed |
| CN-102076650-A | Carboxylic acid compound | DAIICHI SANKYO CO LTD | 2011-05-25 | — | — | CN | disclosed |
| US-20110053974-A1 | CARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2289868-A1 | CARBOXYLIC ACID COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2011-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053974-A1 | CARBOXYLIC ACID COMPOUND | AKR1C3, SLC5A1, GPR119 | CYP11B1 79/4885CYP11B2 106/4885EPAS1 2569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.