Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26650445 | 1.00 | NOTUM (0.41) | NOTUMCYP11B1CYP11B2TRPV1AR | |
| SCHEMBL1508486 | 0.81 | CYP11B1 (0.44) | CYP11B1CYP11B2S1PR1EPAS1 | |
| SCHEMBL9277855 | 0.80 | CYP11B1 (0.40) | CYP11B1CYP11B2ARS1PR1OPRM1 | |
| SCHEMBL22102575 | 0.77 | OPRM1 (0.34) | CYP11B1CYP11B2MAP3K14EPAS1OPRM1 | |
| SCHEMBL11352700 | 0.77 | NOTUM (0.37) | NOTUMCYP11B1CYP11B2ARMAP3K14 | |
| SCHEMBL9280523 | 0.77 | CYP11B1 (0.45) | CYP11B1CYP11B2TRPV1ARS1PR1 | |
| SCHEMBL22102579 | 0.74 | MAP3K14 (0.34) | CYP11B1CYP11B2MAP3K14OPRM1OPRL1 | |
| SCHEMBL15287132 | 0.74 | MAP3K14 (0.34) | CYP11B1CYP11B2S1PR1MAP3K14OPRM1 | |
| SCHEMBL22102913 | 0.74 | OPRL1 (0.37) | CYP11B1CYP11B2MAP3K14OPRM1OPRL1 | |
| SCHEMBL29660414 | 0.74 | MAP3K14 (0.34) | CYP11B1CYP11B2S1PR1MAP3K14OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522596-A1 | DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS | C4X Discovery Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119497712-A | Indane derivatives as MALT1 inhibitors | 希四克斯探索有限公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2023218203-A1 | DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |