Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659469 | 0.84 | ADORA2A (0.35) | ADORA2AFPR2 | |
| SCHEMBL15085706 | 0.83 | ADORA2A (0.31) | ADORA2A | |
| SCHEMBL3660360 | 0.75 | P2RX7 (0.37) | ADORA2A | |
| SCHEMBL10277614 | 0.74 | EPHX2 (0.31) | — | |
| SCHEMBL3660008 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL15295451 | 0.70 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL10277702 | 0.69 | HTR3E (0.34) | — | |
| SCHEMBL15375626 | 0.69 | — | — | |
| SCHEMBL3656722 | 0.69 | ADORA2A (0.41) | ADORA2AFPR2 | |
| SCHEMBL2392985 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445914-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2015-07-22 | — | — | EP | disclosed |
| EP-2445909-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2013-11-13 | — | — | EP | disclosed |
| US-8481750-B2 | Derivatives of 6,7-dihydro-5H-imidazo[1,2-α]imidazole-3-carboxylic acid amides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-09 | — | — | US | disclosed |