Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087654 | 1.00 | SLC7A5 (0.47) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL7745425 | 0.91 | SLC7A5 (0.51) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL7745422 | 0.91 | SLC7A5 (0.51) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2674665 | 0.90 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2931777 | 0.90 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2674668 | 0.90 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2674679 | 0.90 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL23387522 | 0.87 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL30611546 | 0.87 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL15105436 | 0.87 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240024268-A1 | Methods for Dopamine Modulation in Human Neurologic Diseases | SACKNER BERNSTEIN JONATHAN (US) | 2024-01-25 | — | — | US | claimed |
| US-20240016815-A1 | COMPOSITIONS AND METHODS FOR MODULATING CANCER IN NON-HUMAN MAMMALS | HOFFMAN TECHNOLOGIES LLC | 2024-01-18 | — | — | US | claimed |
| US-11806326-B2 | Methods for dopamine modulation in human neurologic diseases | SACKNER BERNSTEIN JONATHAN (US) | 2023-11-07 | — | — | US | claimed |
| US-11786496-B2 | Composition and methods for treating intestinal hyperpermeability | YAMO PHARMACEUTICALS LLC (US) | 2023-10-17 | — | — | US | claimed |
| US-20230141609-A1 | Methods of Treating Amyotrophic Lateral Sclerosis and Symptoms | YAMO PHARMACEUTICALS LLC (US) | 2023-05-11 | — | — | US | claimed |
| US-11534420-B2 | Compositions and methods for treating cancer | TYME, INC. (US) | 2022-12-27 | — | — | US | claimed |
| CN-115515575-A | Tyrosine derivatives for the modulation of cancer | 迪美公司 | 2022-12-23 | — | — | CN | claimed |
| CN-114901272-A | Sustained release preparation | 霍夫曼技术有限责任公司 | 2022-08-12 | — | — | CN | claimed |
| US-20220211650-A1 | SUSTAINED RELEASE FORMULATIONS | HOFFMAN TECHNOLOGIES LLC | 2022-07-07 | — | — | US | claimed |
| EP-3968785-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | Tyme, Inc. (US) | 2022-03-23 | — | — | EP | claimed |
| WO-2015061256-A1 | HIGH-SPEED CENTRIFUGAL MIXING DEVICES AND METHODS OF USE | TYME, INC. (US) | 2015-04-30 | — | — | WO | claimed |
| WO-2015061288-A1 | TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM | TYME, INC. (US) | 2015-04-30 | — | — | WO | claimed |
| US-20150111937-A1 | Compositions and Methods for Treating Intestinal Hyperpermeability | YAMO PHARMACEUTICALS LLC | 2015-04-23 | — | — | US | claimed |
| US-20150111878-A1 | COMPOSITIONS AND METHODS FOR TREATING INTESTINAL HYPERPERMEABILITY | HOFFMAN STEVEN (US) | 2015-04-23 | — | — | US | claimed |
| US-20150110735-A1 | HIGH-SPEED CENTRIFUGAL MIXING DEVICES AND METHODS OF USE | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2015-04-23 | — | — | US | claimed |
| US-20150112116-A1 | TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2015-04-23 | — | — | US | claimed |
| EP-2804599-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | Tyme, Inc. (US) | 2014-11-26 | — | — | EP | claimed |
| WO-2013109610-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | HOFFMAN STEVEN (US) | 2013-07-25 | — | — | WO | claimed |
| US-20130184214-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2013-07-18 | — | — | US | claimed |
| US-8481498-B1 | Pharmaceutical compositions and methods | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2013-07-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220211650-A1 | SUSTAINED RELEASE FORMULATIONS | TH, PAH, COMT | SLC7A5 492/4885MEN1 2080/4885KMT2A 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.