Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2674679 | 1.00 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AADORA3HSD17B10 | |
| SCHEMBL2674668 | 1.00 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AADORA3HSD17B10 | |
| SCHEMBL2674665 | 1.00 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AADORA3HSD17B10 | |
| SCHEMBL28087654 | 0.90 | SLC7A5 (0.47) | SLC7A5MEN1KMT2AADORA3HSD17B10 | |
| SCHEMBL15085708 | 0.90 | SLC7A5 (0.47) | SLC7A5MEN1KMT2AADORA3HSD17B10 | |
| SCHEMBL5379357 | 0.88 | SLC7A5 (0.46) | SLC7A5MEN1KMT2AADORA3HSD17B10 | |
| SCHEMBL9162835 | 0.85 | ALDH1A1 (0.54) | MEN1KMT2APTGS2HTR2BALDH1A1 | |
| SCHEMBL9162838 | 0.85 | ALDH1A1 (0.54) | MEN1KMT2APTGS2HTR2BALDH1A1 | |
| SCHEMBL491220 | 0.84 | LDHA (0.67) | MEN1KMT2AHSD17B10PTGS2HTR2B | |
| SCHEMBL5302134 | 0.84 | SLC7A5 (0.55) | SLC7A5MEN1KMT2AADORA3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576179-B1 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS | IRM LLC (BM) | 2010-09-15 | — | — | EP | disclosed |