Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745425 | 1.00 | SLC7A5 (0.51) | SLC7A5MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL15085708 | 0.91 | SLC7A5 (0.47) | SLC7A5MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL28087654 | 0.91 | SLC7A5 (0.47) | SLC7A5MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL2674679 | 0.82 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL29510634 | 0.82 | SLC7A5 (0.58) | SLC7A5MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL7280620 | 0.82 | THRB (0.56) | SLC7A5MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL2931777 | 0.82 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL2674665 | 0.82 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL2674668 | 0.82 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL15085689 | 0.82 | MEN1 (0.48) | SLC7A5MEN1KMT2AHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735819-B1 | CRYPTOPHYCINS | UNIV HAWAII (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0830136-A4 | NEW CRYPTOPHYCINS FROM SYNTHESIS | UNIV HAWAII (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-0836382-A4 | NEW CRYPTOPHYCINS | UNIV HAWAII (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6013626-A | TO INHIBIT THE PROLIFERATION OF MAMMALIAN CELLS; ANTITUMOR AGENTS | THE UNIVERSITY OF HAWAII (US) | 2000-01-11 | — | — | US | disclosed |
| US-5955423-A | USED TO INHIBIT THE PROLIFERATION OF HYPERPROLIFERATIVE CELLS; DERIVED FROM NOSTOC SP.OF BLUE-GREEN ALGAE | THE UNIVERSITY OF HAWAII (US) | 1999-09-21 | — | — | US | disclosed |
| US-5952298-A | NOVEL CRYPTOPHYCIN COMPOUNDS PRODUCED BY CYANOBACTERIA OF GENUS NOSTOC USED AS ANTIPROLIFERATIVE AGENTS IN COMBINATION WITH ANTIMITOTIC AGENTS TO TREAT CELLS WITH DRUG RESISTANT PHENOTYPES, AND TO TREAT NEOPLASIA | THE UNIVERSITY OF HAWAII (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0836382-A1 | NEW CRYPTOPHYCINS | UNIVERSITY OF HAWAII (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0830136-A1 | NEW CRYPTOPHYCINS FROM SYNTHESIS | UNIVERSITY OF HAWAII (US) | 1998-03-25 | — | — | EP | disclosed |
| EP-0735819-A4 | NEW CRYPTOPHYCINS | UNIV HAWAII (US) | 1997-03-19 | — | — | EP | disclosed |
| WO-1996039829-A9 | NEW CRYPTOPHYCINS | — | 1997-02-20 | — | — | WO | disclosed |
| WO-1996040184-A1 | NEW CRYPTOPHYCINS FROM SYNTHESIS | UNIVERSITY OF HAWAII (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996039829-A1 | NEW CRYPTOPHYCINS | UNIVERSITY OF HAWAII (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0735819-A1 | NEW CRYPTOPHYCINS | UNIVERSITY OF HAWAII (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017093-A1 | NEW CRYPTOPHYCINS | UNIVERSITY OF HAWAII (US) | 1995-06-29 | — | — | WO | disclosed |