Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15085708 | 1.00 | SLC7A5 (0.47) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL7745425 | 0.91 | SLC7A5 (0.51) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL7745422 | 0.91 | SLC7A5 (0.51) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2674665 | 0.90 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2931777 | 0.90 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2674668 | 0.90 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2674679 | 0.90 | SLC7A5 (0.52) | SLC7A5MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL23387522 | 0.87 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL30611546 | 0.87 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL15105436 | 0.87 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105848652-A | Tyrosine hydroxylase inhibitors for the treatment of intestinal hyperpermeability | 史蒂文·霍夫曼 | 2016-08-10 | — | — | CN | disclosed |