SCHEMBL15085779

SCHEMBL15085779

CCOC(=O)c1ccc(-c2ccc(C(=O)Nc3ccc(Oc4ccc(C)cc4)cc3)c(C(=O)O)c2)cc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.53
GFER P55789 1/20 0.53
TDP1 Q9NUW8 2/20 0.49
PNLIP P16233 1/20 0.49
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
CRHBP P24387 2/20 0.46
CRHR2 Q13324 2/20 0.46
HPGD P15428 2/20 0.46
MAPT P10636 2/20 0.46
ALDH1A1 P00352 3/20 0.44
GAA P10253 3/20 0.44
LMNA P02545 2/20 0.44
XDH P47989 1/20 0.44
POLB P06746 1/20 0.44
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13579198 0.84 MAPK1 (0.58) MAPK1GFERTDP1PNLIPMEN1
SCHEMBL20370268 0.82 MAPK1 (0.55) MAPK1GFERTDP1PNLIPMEN1
SCHEMBL9885177 0.81 MAPK1 (0.57) MAPK1GFERTDP1PNLIPMEN1
SCHEMBL6852976 0.81 SMN1; SMN2 (0.59) MAPK1MEN1KMT2AL3MBTL1NPC1
SCHEMBL17268315 0.78 TDP1 (0.50) MAPK1GFERTDP1MEN1KMT2A
SCHEMBL26787527 0.78 MAPK1 (0.55) MAPK1GFERTDP1PNLIPMEN1
SCHEMBL17732429 0.77 F12 (0.49) TDP1MEN1KMT2AL3MBTL1NPC1
SCHEMBL15294833 0.77 MAPK1 (0.63) MAPK1GFERTDP1PNLIPMEN1
SCHEMBL12700426 0.77 GFER (0.78) MAPK1GFERTDP1PNLIPMEN1
SCHEMBL13932543 0.76 PNLIP (0.50) MAPK1GFERPNLIPMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9617223-B2 Base generator ETERNAL MATERIALS CO., LTD. (TW) 2017-04-11 US disclosed
US-20130172569-A1 BASE GENERATOR ETERNAL CHEMICAL CO., LTD. (TW) 2013-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172569-A1 BASE GENERATOR REV1, MUS81, PADI1 MAPK1 2685/4885GFER 457/4885TDP1 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.