SCHEMBL6852976

SCHEMBL6852976

CCOC(=O)c1ccc(NC(=O)c2ccc(-c3ccc(C(=O)O)c(C(=O)O)c3)cc2C(=O)Nc2ccc(C(=O)OCC)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.59
RAB9A P51151 5/20 0.59
GAA P10253 3/20 0.59
NPC1 O15118 3/20 0.59
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
ALDH1A1 P00352 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ALOX15 P16050 1/20 0.55
MAPT P10636 3/20 0.53
TSHR P16473 2/20 0.53
PPARA Q07869 1/20 0.53
GPR35 Q9HC97 1/20 0.53
MAPK1 P28482 1/20 0.51
MAOA P21397 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6853182 0.87 PTPN1 (0.58) SMN1; SMN2RAB9AGAANPC1MEN1
SCHEMBL6852426 0.87 PTPN1 (0.58) SMN1; SMN2RAB9AGAANPC1MEN1
SCHEMBL6851359 0.87 RAB9A (0.64) SMN1; SMN2RAB9ANPC1MEN1KMT2A
SCHEMBL11591954 0.85 SMN1; SMN2 (0.68) SMN1; SMN2RAB9AGAANPC1MEN1
SCHEMBL6852756 0.84 PTPN1 (0.61) SMN1; SMN2RAB9AGAANPC1MEN1
SCHEMBL6852760 0.83 ALDH1A1 (0.53) SMN1; SMN2RAB9ANPC1MEN1KMT2A
SCHEMBL6848464 0.83 ALDH1A1 (0.53) SMN1; SMN2RAB9ANPC1MEN1KMT2A
SCHEMBL15085779 0.81 MAPK1 (0.53) SMN1; SMN2RAB9AGAANPC1MEN1
SCHEMBL6848448 0.80 RAB9A (0.57) SMN1; SMN2RAB9ANPC1MEN1KMT2A
SCHEMBL6851324 0.80 KMT2A (0.56) SMN1; SMN2RAB9ANPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828408-B2 Small coefficient of linear expansion and small water absorbing property, and excellent heat resistance; thermotropic liquid crystalline polymer for engineering plastics SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-07 US disclosed
US-20030083459-A1 Aromatic polyimide ester and method for producing thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2003-05-01 US disclosed