Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | LIG1 | P18858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18625821 | 0.87 | CYP19A1 (0.60) | CYP19A1MGAMGAASIMGAM2 | |
| SCHEMBL20644665 | 0.84 | ESRRG (0.55) | CYP19A1MGAMGAASIMGAM2 | |
| SCHEMBL18625968 | 0.84 | CYP19A1 (0.57) | CYP19A1MGAMGAASIMGAM2 | |
| SCHEMBL18625977 | 0.83 | CYP19A1 (0.55) | CYP19A1MGAMGAASIMGAM2 | |
| SCHEMBL30503332 | 0.83 | CYP19A1 (0.55) | CYP19A1MGAMGAASIMGAM2 | |
| SCHEMBL30531808 | 0.78 | KDM4E (0.53) | CYP19A1MGAMGAASIMGAM2 | |
| SCHEMBL13977955 | 0.78 | CYP19A1 (0.71) | CYP19A1NPC1RAB9AMEN1CASP3 | |
| SCHEMBL3777940 | 0.78 | CYP19A1 (0.66) | CYP19A1NPC1RAB9AMEN1CASP3 | |
| SCHEMBL21286183 | 0.77 | NAMPT (0.57) | CYP19A1NPC1RAB9ANAMPTHDAC8 | |
| SCHEMBL16206235 | 0.77 | CYP19A1 (0.70) | CYP19A1NPC1RAB9AMEN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610263-A1 | Sialic acid dimers | Brossmer, Reinhard (DE) | 2013-07-03 | — | — | EP | disclosed |