Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | SI | P14410 | 6/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NEU4 | Q8WWR8 | 1/20 | 0.39 |
| ▸ | NEU1 | Q99519 | 1/20 | 0.39 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15087738 | 0.84 | CYP19A1 (0.57) | NAMPTSRCMGAMGAASI | |
| SCHEMBL28814269 | 0.78 | ESRRG (0.77) | ESRRGHSP90AA1HSP90AB1S1PR1CYP19A1 | |
| SCHEMBL28814333 | 0.77 | ESRRG (0.71) | ESRRGHSP90AA1HSP90AB1CYP19A1MEN1 | |
| SCHEMBL21026702 | 0.77 | ESRRG (0.50) | ESRRGNAMPTSRCNR1H4CYP19A1 | |
| SCHEMBL29050564 | 0.76 | ALOX5 (0.51) | ESRRGSRCKDM4ESMN1; SMN2HSP90AA1 | |
| SCHEMBL29050514 | 0.75 | KDM4E (0.56) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL27983571 | 0.75 | ESRRG (0.69) | ESRRGHSP90AA1HSP90AB1CYP19A1MEN1 | |
| SCHEMBL18625945 | 0.75 | ALOX5 (0.52) | ESRRGNAMPTSRCMGAMGAA | |
| SCHEMBL27984003 | 0.74 | ESRRG (0.67) | ESRRGHSP90AA1HSP90AB1CYP19A1MEN1 | |
| SCHEMBL23329321 | 0.74 | ESRRG (0.46) | ESRRGGAAKDM4ESMN1; SMN2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464922-B2 | Metalloenzyme inhibitor compounds | NQP 1598, LTD. (US) | 2019-11-05 | — | — | US | disclosed |
| US-20190016700-A1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598, LTD. (KY) | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016700-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | ESRRG 1481/4885NAMPT 481/4885SRC 2574/4885 |
| US-10464922-B2 | Metalloenzyme inhibitor compounds | MMEL1, GPX1, MPO | ESRRG 1481/4885NAMPT 481/4885SRC 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.