Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.45 |
| ▸ | TEK | Q02763 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18625821 | 0.85 | CYP19A1 (0.60) | CYP19A1NPC1RAB9AMGAMGAA | |
| SCHEMBL18625968 | 0.83 | CYP19A1 (0.57) | CYP19A1NPC1RAB9AMGAMGAA | |
| SCHEMBL15087738 | 0.83 | CYP19A1 (0.57) | CYP19A1NPC1RAB9AMGAMGAA | |
| SCHEMBL23386949 | 0.80 | GPR55 (0.57) | MGAMGAASIMGAM2KDR | |
| SCHEMBL3777940 | 0.80 | CYP19A1 (0.66) | CYP19A1NPC1RAB9AKDREPHB4 | |
| Bromide SCHEMBL1887515 | 0.78 | CYP19A1 (0.64) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL16264704 | 0.77 | CYP19A1 (0.62) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL12022152 | 0.77 | CYP19A1 (0.62) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL13977955 | 0.76 | CYP19A1 (0.71) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL21286183 | 0.76 | NAMPT (0.57) | CYP19A1NPC1RAB9AKDREPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593140-B2 | Antibacterial tylosin derivatives and methods for their preparation | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-03-14 | — | — | US | disclosed |