Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15087732 | 0.81 | RAB9A (0.61) | HDAC1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL8328245 | 0.78 | HDAC1 (0.76) | HDAC1ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL5903723 | 0.78 | HDAC1 (1.00) | HDAC1ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL13857534 | 0.77 | HDAC1 (0.73) | HDAC1ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL15090062 | 0.77 | CTSB (0.50) | HDAC1ALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL13044173 | 0.75 | ALDH1A1 (0.68) | HDAC1ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL28799913 | 0.74 | MAPK1 (0.57) | ALDH1A1KDM4ELMNAMAPTRAB9A | |
| SCHEMBL28007421 | 0.74 | MAPK1 (0.57) | ALDH1A1KDM4ELMNAMAPTRAB9A | |
| SCHEMBL28801511 | 0.74 | MAPK1 (0.57) | ALDH1A1KDM4ELMNAMAPTRAB9A | |
| SCHEMBL17921133 | 0.73 | HDAC1 (0.52) | HDAC1ALDH1A1KDM4EL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015128344-A1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2015-09-03 | — | — | WO | disclosed |
| EP-2910561-A1 | Sialic acid derivatives | Brossmer, Reinhard (DE) | 2015-08-26 | — | — | EP | disclosed |
| WO-2013097942-A1 | SIALIC ACID DIMERS | BROSSMER REINHARD (DE) | 2013-07-04 | — | — | WO | disclosed |
| EP-2610263-A1 | Sialic acid dimers | Brossmer, Reinhard (DE) | 2013-07-03 | — | — | EP | disclosed |