Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416283 | 1.00 | MEN1 (0.51) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL5667974 | 0.91 | MEN1 (0.40) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL7118184 | 0.91 | MEN1 (0.40) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL27983412 | 0.84 | TSHR (0.38) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL31695356 | 0.79 | TSHR (0.39) | MEN1KMT2ATHRBHTTMAPT | |
| Ethylene Glycol SCHEMBL5667972 | 0.77 | LMNA (0.38) | MEN1KMT2ATHRBHTTMAPT | |
| Ethylene Glycol SCHEMBL7118182 | 0.77 | LMNA (0.38) | MEN1KMT2ATHRBHTTMAPT | |
| Ethylene Glycol SCHEMBL1509039 | 0.76 | LMNA (0.37) | MEN1KMT2ATHRBHTTMAPT | |
| Ethylene Glycol SCHEMBL8416280 | 0.76 | LMNA (0.37) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8324723 | 0.75 | MEN1 (0.42) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5357636-A | Flexible protective medical gloves and methods for their use | DRESDNER JR KARL P (US) | 1994-10-25 | — | — | US | claimed |
| US-5335373-A | Protective medical gloves and methods for their use | DRESDNER JR KARL P (US) | 1994-08-09 | — | — | US | claimed |
| US-8003076-B2 | Methods for conducting metabolic analyses | TARGET DISCOVERY, INC. (US) | 2011-08-23 | — | — | US | disclosed |
| EP-1084396-B9 | ELECTROPHORESIS APPARATUS AND METHOD | UNIV TEXAS (US) | 2011-07-13 | — | — | EP | disclosed |
| EP-2293056-A2 | A method for analysing a metabolic pathway | Target Discovery, Inc. (US) | 2011-03-09 | — | — | EP | disclosed |
| EP-1084396-B1 | ELECTROPHORESIS APPARATUS AND METHOD | UNIV TEXAS (US) | 2011-03-02 | — | — | EP | disclosed |
| US-20090010915-A1 | Methods for Conducting Metabolic Analyses | TARGET DISCOVERY, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-7435406-B2 | Methods for conducting metabolic analyses | TARGET DISCOVERY, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| EP-1194768-A4 | POLYPEPTIDE FINGERPRINTING METHODS, METABOLIC PROFILING, AND BIOINFORMATICS DATABASE | TARGET DISCOVERY INC (US) | 2008-03-26 | — | — | EP | disclosed |
| US-20080020376-A1 | Enriched Cdna Expression Libraries and Methods of Making and Using Same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-24 | — | — | US | disclosed |
| US-7211376-B2 | Polypeptide fingerprinting methods | TARGET DISCOVERY, INC. (US) | 2007-05-01 | — | — | US | disclosed |
| WO-2002014851-A2 | ELECTROPHORESIS APPARATUS AND METHOD | LYNX THERAPEUTICS, INC. (US) | 2002-02-21 | — | — | WO | disclosed |
| US-6214191-B1 | SEPARATION COMPONENTS WITHIN A SAMPLE | LYNX THERAPEUTICS, INC. | 2001-04-10 | — | — | US | disclosed |
| WO-2000063683-A1 | POLYPEPTIDE FINGERPRINTING METHODS, METABOLIC PROFILING, AND BIOINFORMATICS DATABASE | TARGET DISCOVERY, INC. (US) | 2000-10-26 | — | — | WO | disclosed |
| US-6013165-A | APPARATUS, SYSTEM, AND METHOD FOR TWO DIMENSIONAL ELECTROPHORESIS OF ANALYTES OF INTEREST, PARTICULARLY POLYPEPTIDES | LYNX THERAPEUTICS, INC. (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0738391-A1 | RADIAL FLOW ASSAY | INTRACEL CORPORATION (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5547833-A | Radial flow assay, delivering member, test kit, and methods | INTRACEL CORPORATION (US) | 1996-08-20 | — | — | US | disclosed |
| WO-1995018970-A1 | RADIAL FLOW ASSAY | INTRACEL CORPORATION (US) | 1995-07-13 | — | — | WO | disclosed |
| US-5357636-A | Flexible protective medical gloves and methods for their use | DRESDNER JR KARL P (US) | 1994-10-25 | — | — | US | disclosed |
| US-5335373-A | Protective medical gloves and methods for their use | DRESDNER JR KARL P (US) | 1994-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090010915-A1 | Methods for Conducting Metabolic Analyses | PC, FAH, CYP27A1 | MEN1 866/4885KMT2A 3864/4885THRB 3379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.