⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856415 | 0.71 | — | — | |
| SCHEMBL6693515 | 0.71 | — | — | |
| SCHEMBL12633322 | 0.67 | — | — | |
| SCHEMBL278150 | 0.63 | CHRM2 (0.52) | — | |
| SCHEMBL1055704 | 0.63 | — | — | |
| SCHEMBL9550315 | 0.61 | CTSL (0.35) | — | |
| SCHEMBL317538 | 0.61 | PARL (0.34) | — | |
| SCHEMBL9534525 | 0.61 | CHRM2 (0.31) | — | |
| SCHEMBL717282 | 0.61 | BRD4 (0.35) | — | |
| SCHEMBL8471148 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754764-B | anti-DOG-1 antibodies, conjugates, pharmaceutical compositions, pharmaceutical formulations and uses thereof | 四川大学华西医院 | 2022-09-06 | — | — | CN | claimed |
| EP-1476489-B8 | HYDROLYTICALLY DEGRADABLE ALKYLENE OXIDE BASED POLYMERS | NEKTAR THERAPEUTICS AL CORP (US) | 2008-10-08 | — | — | EP | claimed |
| EP-1476489-B1 | HYDROLYTICALLY DEGRADABLE ALKYLENE OXIDE BASED POLYMERS | NEKTAR THERAPEUTICS AL CORP (US) | 2008-04-09 | — | — | EP | claimed |
| US-20060239961-A1 | Hydrolytically degradable alkylene oxide based polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2006-10-26 | — | — | US | claimed |
| EP-1476489-A1 | HYDROLYTICALLY DEGRADABLE ALKYLENE OXIDE BASED POLYMERS | Nektar Therapeutics Al, Corporation (US) | 2004-11-17 | — | — | EP | claimed |
| WO-2003070805-A1 | HYDROLYTICALLY DEGRADABLE ALKYLENE OXIDE BASED POLYMERS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2003-08-28 | — | — | WO | claimed |
| US-20030023023-A1 | Hydrolytically degradable polymers and hydrogels made therefrom | SHEARWATER CORPORATION | 2003-01-30 | — | — | US | claimed |
| US-6348558-B1 | OLIGOMERS COMPRISING ALKYLENE OXIDE MONOMERS AND CARBONATE LINKAGES; POLYCARBONATEETHER COPOLYMERS; DRUG DELIVERY; CONJUGATED TO PEPTIDES OR PROTEINS FOR REDUCED IMMUNOGENICITY; STABILITY | SHEARWATER CORPORATION | 2002-02-19 | — | — | US | claimed |
| EP-0445862-B1 | N-(4-piperidinyl)(dihydrobenzofuran or dihydro-2H-benzopyran)carboxamide derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2000-04-19 | — | — | EP | claimed |
| CN-116459352-B | DNA condensation system, non-unwinding cyclic compound, preparation method and application in preparation of gene therapy medicine | 嘉兴清准医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-111558049-B | Methylene carbamate linkers for use with target-drug conjugates | 西雅图基因公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-111569086-B | Methylene carbamate linkers for use with target-drug conjugates | 西雅图基因公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20240115655-A1 | DOSING REGIMENS AND RELATED COMPOSITIONS AND METHODS | SIXTH STREET LENDING PARTNERS | 2024-04-11 | — | — | US | disclosed |
| CN-109562152-B | Drug conjugates containing self-stabilizing linkers with improved physiochemical properties | 西雅图基因公司 | 2024-04-02 | — | — | CN | disclosed |
| US-6800728-B2 | CROSSLINKING AND IMMOBILIZING BIOMOLECULES, DRUGS AND SYNTHETIC POLYMERS WITH A THIOL OR AMINO REACTIVE GROUP AND HYDRAZINO OR OXYAMINO MOIETIES | SOLULINK BIOSCIENCES, INC. | 2004-10-05 | — | — | US | disclosed |
| US-20040110730-A1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | AUDAX PRIVATE DEBT LLC, AS AGENT | 2004-06-10 | — | — | US | disclosed |
| EP-1315699-A2 | HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS | Solulink, Incorporated (US) | 2003-06-04 | — | — | EP | disclosed |
| US-20030013857-A1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | SOLULINK INCORPORATED | 2003-01-16 | — | — | US | disclosed |
| WO-2002100343-A2 | N-TERMINALLY TRUNCATED GALECTIN-3 AND ANTIBODIES FOR TREATING CANCER | MANDALMED, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| WO-2001070685-A2 | HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS | SOLULINK, INCORPORATED (US) | 2001-09-27 | — | — | WO | disclosed |