Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983055 | 0.92 | TSHR (0.50) | TSHRHCRTR1ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL15092695 | 0.90 | ALDH1A1 (0.51) | TSHRCDC25BALDH1A1L3MBTL1KDM4E | |
| SCHEMBL15092983 | 0.87 | TSHR (0.54) | TSHRALDH1A1HSD17B10L3MBTL1KDM4E | |
| SCHEMBL15092737 | 0.86 | TSHR (0.44) | TSHRCDC25BHCRTR1ALDH1A1L3MBTL1 | |
| SCHEMBL1979142 | 0.85 | LMNA (0.45) | TSHRHCRTR1ALDH1A1HSD17B10ABCB1 | |
| SCHEMBL14244316 | 0.85 | TSHR (0.53) | TSHRCDC25BALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL15092822 | 0.85 | ALDH1A1 (0.42) | TSHRCDC25BHCRTR1ALDH1A1HSD17B10 | |
| SCHEMBL15093081 | 0.84 | ALDH1A1 (0.40) | TSHRCDC25BALDH1A1L3MBTL1KDM4E | |
| SCHEMBL15092731 | 0.84 | ELANE (0.41) | TSHRCDC25BHCRTR1ALDH1A1KDM4E | |
| SCHEMBL15093123 | 0.84 | CDC25B (0.44) | TSHRCDC25BHCRTR1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729312-B2 | Derivatives of novel peroxides, method of preparation thereof and use thereof in human medicine as well as in cosmetics for the treatment or prevention of acne | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-05-20 | — | — | US | claimed |
| US-20130178648-A1 | DERIVATIVES OF NOVEL PEROXIDES, METHOD OF PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AS WELL AS IN COSMETICS FOR THE TREATMENT OR PREVENTION OF ACNE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178648-A1 | DERIVATIVES OF NOVEL PEROXIDES, METHOD OF PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AS WELL AS IN COSMETICS FOR THE TREATMENT OR PREVENTION OF ACNE | GPX4, LPO, GPX1 | TSHR 2165/4885CDC25B 1244/4885HCRTR1 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.