Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | CTSL | P07711 | 4/20 | 0.57 |
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | CTSK | P43235 | 3/20 | 0.57 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGDS | O60760 | 2/20 | 0.54 |
| ▸ | CTSV | O60911 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16523134 | 0.92 | CTSL (0.65) | PTPN1CTSLCTSSCTSKCTSB | |
| SCHEMBL4684065 | 0.91 | HPGDS (0.65) | PTPN1CTSLCTSSCTSKCTSB | |
| SCHEMBL10526607 | 0.91 | PTPN1 (0.70) | PTPN1CTSLCTSSCTSKCTSB | |
| SCHEMBL4166657 | 0.91 | PTPN1 (0.70) | PTPN1CTSLCTSSCTSKCTSB | |
| SCHEMBL4682004 | 0.91 | PTPN1 (0.70) | PTPN1CTSLCTSSCTSKCTSB | |
| SCHEMBL26820570 | 0.87 | GAA (0.73) | PTPN1CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL4175147 | 0.87 | GAA (0.73) | PTPN1CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL16768861 | 0.85 | PTPN1 (0.66) | PTPN1CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL4028404 | 0.84 | ALDH1A1 (0.57) | CTSSCTSKL3MBTL1RAB9ANPC1 | |
| SCHEMBL4291861 | 0.84 | ALDH1A1 (0.57) | CTSSCTSKL3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9410148-B2 | Method for constructing libraries of non-standard peptide compounds comprising N-methyl amino acids and other special (non-standard) amino acids and method for searching and identifying active species | THE UNIVERSITY OF TOKYO (JP) | 2016-08-09 | — | — | US | disclosed |
| US-20130178394-A1 | METHOD FOR CONSTRUCTING LIBRARIES OF NON-STANDARD PEPTIDE COMPOUNDS COMPRISING N-METHYL AMINO ACIDS AND OTHER SPECIAL (NON-STANDARD) AMINO ACIDS AND METHOD FOR SEARCHING AND IDENTIFYING ACTIVE SPECIES | THE UNIVERSITY OF TOKYO (JP) | 2013-07-11 | — | — | US | disclosed |