SCHEMBL1509713

SCHEMBL1509713

[CH]=Cc1cccc(C)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.42
ATM Q13315 1/20 0.42
ALDH1A1 P00352 7/20 0.41
TSHR P16473 3/20 0.41
CYP2A6 P11509 2/20 0.38
CYP1A2 P05177 1/20 0.38
ACHE P22303 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
ADRB1 P08588 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 2/20 0.32
RAPGEF4 Q8WZA2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7114535 0.80 TRPA1 (0.42) TRPA1ATMALDH1A1TSHRCYP2A6
SCHEMBL3306781 0.79 TRPA1 (0.46) TRPA1ATMALDH1A1TSHRCYP2A6
SCHEMBL6546426 0.79 TRPA1 (0.46) TRPA1ATMALDH1A1TSHRCYP2A6
SCHEMBL207316 0.79
SCHEMBL4318496 0.79 TRPA1 (0.46) TRPA1ATMALDH1A1TSHRCYP2A6
SCHEMBL5257066 0.78 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL3514534 0.77 KDM4E (0.33) TSHRCYP2A6CYP1A2MAPTKDM4E
SCHEMBL1609965 0.77 TRPA1 (0.44) TRPA1ATMALDH1A1TSHRCYP2A6
SCHEMBL6062174 0.75 TRPA1 (0.42) TRPA1ATMALDH1A1TSHRCYP2A6
SCHEMBL29444 0.75 TSHR (0.65) TRPA1ATMALDH1A1TSHRCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3707231-A1 ANTI-FOAM COMPOSITIONS The Procter and Gamble Company (US) 2020-09-16 EP claimed
EP-2078054-A1 TIRE FOR VEHICLE WHEELS COMPRISING CROSSLINKED ELASTOMERIC COMPOSITION Pirelli Tyre S.p.A. (IT) 2009-07-15 EP claimed
WO-2008052571-A1 TIRE FOR VEHICLE WHEELS COMPRISING CROSSLINKED ELASTOMERIC COMPOSITION PIRELLI TYRE S.P.A. (IT) 2008-05-08 WO claimed
US-11739208-B2 Block copolymers and uses thereof Kraton Corporation (US) 2023-08-29 US disclosed
EP-3960780-A1 BLOCK COPOLYMERS AND USES THEREOF Kraton Polymers Research B.V. (NL) 2022-03-02 EP disclosed
US-20220049083-A1 Novel Block Copolymers and Uses Thereof KRATON POLYMERS LLC (US) 2022-02-17 US disclosed
EP-2295592-B1 An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin NIPPON CATALYTIC CHEM IND (JP) 2012-12-26 EP disclosed
EP-1160329-B1 An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin NIPPON CATALYTIC CHEM IND (JP) 2011-04-06 EP disclosed
EP-2295592-A1 An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin Nippon Shokubai Co., Ltd. (JP) 2011-03-16 EP disclosed
EP-2078054-A1 TIRE FOR VEHICLE WHEELS COMPRISING CROSSLINKED ELASTOMERIC COMPOSITION Pirelli Tyre S.p.A. (IT) 2009-07-15 EP disclosed
WO-2008052571-A1 TIRE FOR VEHICLE WHEELS COMPRISING CROSSLINKED ELASTOMERIC COMPOSITION PIRELLI TYRE S.P.A. (IT) 2008-05-08 WO disclosed
US-5382497-A Optical recording medium and process for recording thereupon CANON KABUSHIKI KAISHA (JP) 1995-01-17 US disclosed
US-5320930-A Irradiating to form detectable pits; containing pyrylium, cyanine, merocyanine dyes, selenapyrylium and methine dyes CANON KABUSHIKI KAISHA (JP) 1994-06-14 US disclosed
US-5278026-A Comprising photosensitive compounds CANON KABUSHIKI KAISHA (JP) 1994-01-11 US disclosed
US-5246814-A Mehtine or pyrylium dye CANON KABUSHIKI KAISHA (JP) 1993-09-21 US disclosed
EP-0264198-B1 OPTICAL INFORMATION RECORDING MEDIUM CANON KABUSHIKI KAISHA (JP) 1993-03-03 EP disclosed
US-5178995-A Reflectance, storage stability CANON KABUSHIKI KAISHA (JP) 1993-01-12 US disclosed
US-5079127-A Methine Dyes CANON KABUSHIKI KAISHA (JP) 1992-01-07 US disclosed
US-5079128-A Thin film containing a methine dye having at least two dimethylaminophenyl groups and a carbonium ion; laser writing; heat resistance CANON KABUSHIKI KAISHA (JP) 1992-01-07 US disclosed
EP-0264198-A2 Optical information recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP disclosed