Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046008 | 0.78 | KDM4E (0.35) | KDM4EMAPTMAPK1CYP1A2CYP2A6 | |
| SCHEMBL1509713 | 0.77 | TRPA1 (0.42) | KDM4EMAPTCYP1A2CYP2A6TSHR | |
| SCHEMBL1613096 | 0.76 | KDM4E (0.34) | KDM4EMAPTMAPK1CYP1A2CYP2A6 | |
| SCHEMBL6534927 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL366594 | 0.74 | ALDH1A1 (0.48) | KDM4EMAPTCYP1A2CYP2A6TSHR | |
| SCHEMBL16957541 | 0.74 | KDM4E (0.38) | KDM4EMAPTMAPK1CYP1A2CYP2A6 | |
| SCHEMBL57999 | 0.74 | MAPT (0.33) | KDM4EMAPTMAPK1CYP1A2CYP2A6 | |
| SCHEMBL5494672 | 0.72 | TSHR (0.45) | KDM4EMAPTMAPK1CYP1A2CYP2A6 | |
| SCHEMBL37955 | 0.72 | TSHR (0.45) | KDM4EMAPTMAPK1CYP1A2CYP2A6 | |
| Ethylene SCHEMBL27864741 | 0.72 | KDM4E (0.32) | KDM4EMAPTMAPK1CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647744-B2 | Graphite clay composite material, process for producing the same, gasket or packing comprising the composite material, and clay dispersion used for the composite material | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
| US-20090295103-A1 | GRAPHITE CLAY COMPOSITE MATERIAL, PROCESS FOR PRODUCING THE SAME, GASKET OR PACKING COMPRISING THE COMPOSITE MATERIAL, AND CLAY DISPERSION USED FOR THE COMPOSITE MATERIAL | NATIONAL INSTITUTE OF ACVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2009-12-03 | — | — | US | disclosed |
| CN-101432135-A | Graphite clay composite, process for producing the same, gasket or packing based on the composite, and clay dispersion liquid used for the composite | NAT INST OF ADVANCED IND SCIEN (JP) | 2009-05-13 | — | — | CN | disclosed |
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. | 2008-02-07 | — | — | US | disclosed |
| US-7256211-B1 | 8-azaprostaglandin derivatives and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-14 | — | — | US | disclosed |
| US-20070167490-A1 | Imino ether derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO LTD | 2007-07-19 | — | — | US | disclosed |
| US-20070105959-A1 | Cynnamyl alcohol derivative compounds and drugs containing the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| CN-1787989-A | Imino ether derivative compound and medicine containing the same as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2006-06-14 | — | — | CN | disclosed |
| EP-1661879-A1 | DIPHENYL ETHER COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
| EP-1604971-A1 | CINNAMYL ALCOHOL DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1602642-A1 | IMINO ETHER DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-1586564-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICINAL USES THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167490-A1 | Imino ether derivative compounds and drugs containing the compounds as the active ingredient | INSR, NR1H2, NR1H3 | KDM4E 2453/4885MAPT 4616/4885MAPK1 1551/4885 |
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | PPARG, PPARD, PPARA | KDM4E 1577/4885MAPT 4535/4885MAPK1 591/4885 |
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | HPGDS, PTGIS, PTGER4 | KDM4E 2594/4885MAPT 1798/4885MAPK1 1378/4885 |
| US-20070105959-A1 | Cynnamyl alcohol derivative compounds and drugs containing the compounds as active ingredient | LPL, GPR119, EBP | KDM4E 2165/4885MAPT 2722/4885MAPK1 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.