Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 3/20 | 0.41 |
| ▸ | XIAP | P98170 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1409459 | 0.84 | SIGMAR1 (0.68) | SIGMAR1CA12CA1CA2CA7 | |
| SCHEMBL10556615 | 0.79 | SIGMAR1 (0.72) | SIGMAR1HPGDCCNCCDK8ALDH1A1 | |
| SCHEMBL14466291 | 0.78 | SIGMAR1 (0.60) | SIGMAR1CA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL10558570 | 0.78 | SIGMAR1 (0.70) | SIGMAR1HPGDCCNCCDK8ALDH1A1 | |
| Aminobenzoic Acid SCHEMBL865516 | 0.75 | TSHR (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20261717 | 0.72 | CA12 (0.73) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8358137 | 0.72 | SIGMAR1 (0.81) | SIGMAR1HPGDALDH1A1MKNK1MKNK2 | |
| SCHEMBL5874652 | 0.72 | LMNA (0.42) | SIGMAR1CA12CA1CA2CA7 | |
| SCHEMBL20421677 | 0.72 | MEN1 (0.47) | ALPLALDH1A1MEN1LMNAMAPT | |
| SCHEMBL13727453 | 0.71 | HPGD (0.49) | SIGMAR1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289962-A2 | Polyurea compositions and compounds for the preparation thereof | Sawyer, Kenneth I. (US) | 2011-03-02 | — | — | EP | disclosed |