SCHEMBL5874652

SCHEMBL5874652

Nc1ccc(C(=O)ON2CCNCC2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAOA P21397 1/20 0.42
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 2/20 0.42
ESR1 P03372 1/20 0.42
OPRD1 P41143 2/20 0.40
TSHR P16473 2/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PDE4D Q08499 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
USP2 O75604 1/20 0.37
PHLPP2 Q6ZVD8 1/20 0.37
CCNC P24863 1/20 0.37
CDK8 P49336 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11128974 0.88 LMNA (0.48) LMNACYP1A2CYP3A4MAOAALDH1A1
SCHEMBL11197360 0.85 CA12 (0.44) LMNACYP1A2ALDH1A1HSD17B10ESR1
SCHEMBL24120719 0.83 SIGMAR1 (0.56) LMNAALDH1A1HSD17B10OPRD1TSHR
SCHEMBL5874597 0.83 LMNA (0.44) LMNACYP1A2CYP3A4MAOAALDH1A1
SCHEMBL4522298 0.83 SIGMAR1 (0.56) LMNAALDH1A1HSD17B10OPRD1TSHR
SCHEMBL21467212 0.81 SIGMAR1 (0.54) LMNAALDH1A1HSD17B10OPRD1TSHR
SCHEMBL28083939 0.81 SIGMAR1 (0.54) LMNAALDH1A1HSD17B10OPRD1TSHR
SCHEMBL27383717 0.81 SIGMAR1 (0.54) LMNAALDH1A1HSD17B10OPRD1TSHR
SCHEMBL6885871 0.80 GAA (0.47) LMNACYP1A2ALDH1A1HSD17B10OPRD1
SCHEMBL9665160 0.78 SIGMAR1 (0.46) CYP1A2CYP3A4ALDH1A1HSD17B10OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101040028-B Photocrosslinkable materials ROLIC AG 2012-03-28 CN claimed
CN-101040028-A Photocrosslinkable materials ROLIC AG (CH) 2007-09-19 CN claimed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
CN-108912011-B Photoalignment material 罗立克科技股份公司 2021-09-24 CN disclosed
CN-107011924-B Photoalignment materials with side substitution 罗利克有限公司 2021-06-01 CN disclosed
CN-104649916-B Photocrosslinkable materials 罗利克有限公司 2020-12-01 CN disclosed
CN-111533668-A Cyanostilbenes 罗利克技术有限公司 2020-08-14 CN disclosed
CN-103702970-B photoalignment material 罗利克有限公司 2018-10-19 CN disclosed
CN-106873249-B Light alignment materials with side draw generation 罗利克有限公司 2018-09-14 CN disclosed
CN-108350363-A Can photo-alignment material composition 罗利克技术有限公司 2018-07-31 CN disclosed
CN-108350174-A Photo-alignment material 罗利克技术有限公司 2018-07-31 CN disclosed
CN-103842329-A Photoaligning materials ROLIC AG 2014-06-04 CN disclosed
CN-103748192-A Photoreactive compounds ROLIC AG 2014-04-23 CN disclosed
CN-103702970-A photoalignment material ROLIC AG 2014-04-02 CN disclosed
CN-102858849-A Photoaligning material ROLIC AG 2013-01-02 CN disclosed
CN-102753605-A Photoalignment materials with side substitution ROLIC AG 2012-10-24 CN disclosed
CN-101040028-B Photocrosslinkable materials ROLIC AG 2012-03-28 CN disclosed
CN-101040028-A Photocrosslinkable materials ROLIC AG (CH) 2007-09-19 CN disclosed
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed