SCHEMBL150974

SCHEMBL150974

N#Cc1ccc(N(C2CCCCC2)C2CCCCC2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
MCOLN3 Q8TDD5 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
EPHX1 P07099 1/20 0.41
HRH3 Q9Y5N1 2/20 0.40
CYP19A1 P11511 3/20 0.39
ALDH1A1 P00352 2/20 0.37
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
CYP2A6 P11509 1/20 0.35
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA6 P23280 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12733187 0.90 MAOA (0.40) MAOAMAOBNPC1RAB9AHRH3
SCHEMBL4492651 0.83 HRH4 (0.38) NPC1RAB9AHRH3ALDH1A1SMN1; SMN2
SCHEMBL148917 0.81 MAOA (0.46) MAOAMAOBMCOLN3NPC1RAB9A
SCHEMBL154345 0.78 MAOA (0.42) MAOAMAOBMCOLN3NPC1RAB9A
SCHEMBL15031168 0.77 HRH3 (0.47) NPC1RAB9AHRH3ALDH1A1SMN1; SMN2
SCHEMBL14817555 0.77 HRH3 (0.47) NPC1RAB9AHRH3ALDH1A1SMN1; SMN2
SCHEMBL149260 0.75 CTSK (0.39) MCOLN3CTSK
SCHEMBL7873766 0.75 CCNK (0.47) MAOAMAOBMCOLN3NPC1RAB9A
SCHEMBL3698294 0.74 ALDH1A1 (0.39) NPC1RAB9AEPHX1HRH3CYP19A1
SCHEMBL8185165 0.74 TRPM8 (0.44) NPC1RAB9AEPHX1HRH3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8735494-B2 Polymers functionalized with nitrile compounds containing a protected amino group BRIDGESTONE CORPORATION (JP) 2014-05-27 US disclosed
US-20130085227-A1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2013-04-04 US disclosed
US-8344066-B2 Polymers functionalized with nitrile compounds containing a protected amino group BRIDGESTONE CORPORATION (JP) 2013-01-01 US disclosed
US-20120059112-A1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS COMTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2012-03-08 US disclosed
EP-2382240-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP Bridgestone Corporation (JP) 2011-11-02 EP disclosed
WO-2010085622-A9 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2010-12-23 WO disclosed
WO-2010085622-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2010-07-29 WO disclosed