SCHEMBL15097615

SCHEMBL15097615

COSc1ccc(C(C)C)c([N+](=O)[O-])c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.48
ALDH1A1 P00352 4/20 0.35
HPGD P15428 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MCOLN3 Q8TDD5 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
DTYMK P23919 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
HCAR3 P49019 1/20 0.33
HTT P42858 1/20 0.33
TXNRD1 Q16881 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15097628 0.79 ALOX15 (0.36) PDK1ALDH1A1NPSR1MEN1KMT2A
SCHEMBL14154117 0.76 ALDH1A1 (0.53) PDK1ALDH1A1NPSR1MCOLN3MEN1
SCHEMBL15097484 0.75 ALDH1A1 (0.43) ALDH1A1HPGDNPSR1MEN1KMT2A
SCHEMBL20364501 0.73 PDK1 (0.55) PDK1ALDH1A1HPGDNPSR1MCOLN3
SCHEMBL2436246 0.73 TSHR (0.62) PDK1ALDH1A1MEN1KMT2ATDP1
SCHEMBL9735630 0.73 PDK1 (0.55) PDK1ALDH1A1HPGDNPSR1MCOLN3
SCHEMBL2318709 0.71 PDK1 (0.54) PDK1ALDH1A1HPGDNPSR1MCOLN3
SCHEMBL10019193 0.71 PDK1 (0.58) PDK1ALDH1A1HPGDNPSR1TDP1
SCHEMBL15097617 0.71 GABRA1 (0.31) CYP3A4
SCHEMBL16951270 0.71 PDK1 (0.54) PDK1ALDH1A1HPGDNPSR1MCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130177851-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-11 US disclosed