Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965521 | 0.95 | SLC40A1 (0.40) | SLC40A1L3MBTL1RAB9AKDM4ELMNA | |
| SCHEMBL967454 | 0.90 | L3MBTL1 (0.39) | L3MBTL1RAB9AKDM4ELMNAHTT | |
| SCHEMBL6985519 | 0.82 | RELA (0.38) | SLC40A1L3MBTL1RAB9AKDM4ELMNA | |
| SCHEMBL6987201 | 0.80 | CCR1 (0.40) | SLC40A1L3MBTL1RAB9AKDM4ELMNA | |
| SCHEMBL6975182 | 0.78 | L3MBTL1 (0.40) | SLC40A1L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL5819956 | 0.72 | DAO (0.36) | L3MBTL1RAB9AKDM4ELMNANPC1 | |
| SCHEMBL6978820 | 0.71 | KDM4E (0.37) | L3MBTL1RAB9AKDM4ELMNAHTT | |
| SCHEMBL6985131 | 0.71 | KDM4E (0.37) | L3MBTL1RAB9AKDM4ELMNAHTT | |
| SCHEMBL1509598 | 0.70 | LMNA (0.43) | SLC40A1L3MBTL1KDM4ELMNAHTT | |
| SCHEMBL6984797 | 0.68 | MAPK1 (0.38) | L3MBTL1RAB9AKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298301-A2 | Medicaments for increasing endogenous Erythropoietin (EPO) | Fibrogen, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |